TPP1 Antikörper (N-Term)

Produktnummer ABIN1539423

Der Kaninchen Polyklonal anti-TPP1 Antikörper (Klon RB36843) (ABIN1539423) detektiert spezifisch TPP1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für TPP1 Antikörper (N-Term) (ABIN1539423)

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB36843

Produktdetails anti-TPP1 Antikörper

Bindungsspezifität: AA 6-34, N-Term

Homologie: Pr

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human TPP1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: TPP1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu TPP1

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Andere Bezeichnung: TPP1

Hintergrund: This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.

Molekulargewicht: 61248

Gen-ID: 1200

NCBI Accession: NP_000382

UniProt: O14773

Pathways: Zellzyklus, ER-Nucleus Signaling