TPP1 Antikörper (AA 284-563)

Produktnummer ABIN6149442

Produktdetails anti-TPP1 Antikörper

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Bindungsspezifität: AA 284-563

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GANISTWVYS SPGRHEGQEP FLQWLMLLSN ESALPHVHTV SYGDDEDSLS SAYIQRVNTE LMKAAARGLT LLFASGDSGA GCWSVSGRHQ FRPTFPASSP YVTTVGGTSF QEPFLITNEI VDYISGGGFS NVFPRPSYQE EAVTKFLSSS PHLPPSSYFN ASGRAYPDVA ALSDGYWVVS NRVPIPWVSG TSASTPVFGG ILSLINEHRI LSGRPPLGFL NPRLYQQHGA GLFDVTRGCH ESCLDEEVEG QGFCSGPGWD PVTGWGTPNF PALLKTLLNP

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 284-563 of human TPP1 (NP_000382.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TPP1

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Andere Bezeichnung: TPP1 (TPP1 Produkte)

Synonyme: cln2 antikoerper, fa01b09 antikoerper, im:7149243 antikoerper, wu:fa01b09 antikoerper, CLN2 antikoerper, LPIC antikoerper, TPP-1 antikoerper, TPP-I antikoerper, Cln2 antikoerper, tripeptidyl peptidase I antikoerper, tripeptidyl-peptidase 1 antikoerper, tripeptidyl peptidase 1 antikoerper, tpp1 antikoerper, NAEGRDRAFT_78259 antikoerper, MCYG_00184 antikoerper, MGYG_05881 antikoerper, MGYG_00757 antikoerper, TPP1 antikoerper, Tpp1 antikoerper

Hintergrund: This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.,TPP1,CLN2,GIG1,LPIC,SCAR7,TPP-1,Cell Biology & Developmental Biology,Ubiquitin,Neuroscience,Neurodegenerative Diseases,TPP1

Molekulargewicht: 34 kDa/61 kDa

Gen-ID: 1200

UniProt: O14773

Pathways: Zellzyklus, ER-Nucleus Signaling