alpha Adaptin Antikörper (AA 706-727)

Produktnummer ABIN5539681

Produktdetails anti-alpha Adaptin Antikörper

Target: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Bindungsspezifität: AA 706-727

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser alpha Adaptin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: AP2A1 (aa706-727)

Sequenz: ELEPPAPESP MALLADPAPA AD

Spezifität: This antibody is expected to recognize reported isoform 1 (NP_055018.2) only.

Kreuzreaktivität: Rind (Kuh), Human, Maus, Schwein, Ratte

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Güteklasse: Verified

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Western Blot: Approx 110 kDa band observed in Human Brain (Frontal cortex) lysates (calculated MW of 108 kDa according to NP_055018.2). Recommended concentration: 0.03-0.1 μg/mL. Primary incubation was 1 hour.

Peptide ELISA: antibody detection limit dilution 1:128000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Referenzen für anti-alpha Adaptin Antikörper (ABIN5539681)

Buser, Ritz, Moes, Tostado, Frank, Spiess, Mariani, Jenö, Boulay, Hutter: "Quantitative proteomics reveals reduction of endocytic machinery components in gliomas." in: EBioMedicine, Vol. 46, pp. 32-41, (2020) (PubMed).

Details zu alpha Adaptin

Target: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Andere Bezeichnung: AP2A1 (AP2A1 Produkte)

Synonyme: ADTAA antikoerper, AP2-ALPHA antikoerper, CLAPA1 antikoerper, adtaa antikoerper, clapa1 antikoerper, ap2-alpha antikoerper, AP2A1 antikoerper, Adtaa antikoerper, adaptor related protein complex 2 alpha 1 subunit antikoerper, adaptor-related protein complex 2, alpha 1 subunit antikoerper, AP-2 complex subunit alpha-1 antikoerper, AP2A1 antikoerper, ap2a1 antikoerper, Ap2a1 antikoerper, EDI_093420 antikoerper, EDI_259990 antikoerper

Hintergrund: AP2A1, adaptor-related protein complex 2, alpha 1 subunit, ADTAA, AP2-ALPHA, CLAPA1, 100 kDa coated vesicle protein A, AP-2 complex subunit alpha-1, adapter-related protein complex 2 alpha-1 subunit, adaptin, alpha A, adaptor protein complex AP-2 subunit

Gen-ID: 160, 11771, 308578

NCBI Accession: NP_055018

Pathways: Notch Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation