alpha Adaptin Antikörper

Produktnummer ABIN1681069

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch alpha Adaptin in WB und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für alpha Adaptin Antikörper (ABIN1681069)

Target: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser alpha Adaptin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-alpha Adaptin Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human AP2A1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu alpha Adaptin

Target: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Andere Bezeichnung: AP2A1

Hintergrund: This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined. [provided by RefSeq, Jul 2008],ADTAA, AP2-ALPHA, CLAPA1,Cell Biology & Developmental Biology,Neurodegenerative Diseases,Neuroscience,Notch Signaling Pathway,Signal Transduction,AP2A1

Molekulargewicht: 108 kDa

Gen-ID: 160

UniProt: O95782

Pathways: Notch Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation