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alpha Adaptin Antikörper (Adaptor-Related Protein Complex 2, alpha 1 Subunit) AA 3-14 Primary Antibody

AP2A1 Reaktivität: Human ELISA, WB Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN129553
$658.50
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
100 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 1 bis 2 Werktagen
  • Target Alle alpha Adaptin (AP2A1) Antikörper anzeigen
    alpha Adaptin (AP2A1)
    Bindungsspezifität
    • 9
    • 9
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3-14
    Reaktivität
    • 46
    • 17
    • 14
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 34
    • 9
    • 4
    Ziege
    Klonalität
    • 39
    • 8
    Polyklonal
    Konjugat
    • 22
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser alpha Adaptin Antikörper ist unkonjugiert
    Applikation
    • 37
    • 26
    • 26
    • 8
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Kreuzreaktivität
    Schimpanse, Orang-Utan, Maus, Ratte (Rattus), Huhn, Hund
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 3-14 of Human AP2A1 and AP2A2 proteins.
    Isotyp
    IgG
  • Applikationshinweise
    This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 104-107 kDa in size corresponding to AP2A1 or AP2A2 proteins by western blotting in the appropriate cell lysate or extract. Multiple isoforms of each subunit exist for these proteins. The immunogen sequence is found in both AP2A1 and AP2A2. This antibody recognizes a band of approximately 100 kDa in multiple human cell lines and specific reactivity can be blocked with the immunizing peptide.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.7 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    alpha Adaptin (AP2A1)
    Andere Bezeichnung
    AP2A (AP2A1 Produkte)
    Synonyme
    ADTAA, AP2-ALPHA, CLAPA1, adtaa, clapa1, ap2-alpha, AP2A1, Adtaa, adaptor related protein complex 2 alpha 1 subunit, adaptor-related protein complex 2, alpha 1 subunit, AP-2 complex subunit alpha-1, AP2A1, ap2a1, Ap2a1, EDI_093420, EDI_259990
    Hintergrund
    The AP2A1 and AP2A2 represent the AP2 alpha proteins that are found in the AP2 complex in clathrin-coated vesicles. AP2A is also known as Alpha-adaptin A, Adaptor protein complex AP-2 alpha-1 subunit, Clathrin assembly protein complex 2 alpha-A large chain, 100 kDa coated vesicle protein A and Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit.  The AP2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles, which link clathrin to receptors in vesicles.
    Synonyms: AP-2 complex subunit alpha-1, Adapter-related protein complex 2 alpha-1 subunit, Adaptor protein complex AP-2 subunit alpha-1 Alpha1-adaptin, Plasma membrane adaptor HA2/AP2 Clathrin assembly protein complex 2 alpha-A large chain
    Gen-ID
    161, 27477041
    NCBI Accession
    NP_036437
    UniProt
    O95782
    Pathways
    Notch Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation
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