FGFRL1 Antikörper (N-Term)

Produktnummer ABIN5536615

Produktdetails anti-FGFRL1 Antikörper

Target: FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

Bindungsspezifität: AA 131-160, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGFRL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FGFRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-160 amino acids from the N-terminal region of human FGFRL1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For IHC-P starting dilution is: 1:10~50

For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu FGFRL1

Target: FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

Andere Bezeichnung: FGFRL1 (FGFRL1 Produkte)

Synonyme: fgfrl1 antikoerper, zgc:64084 antikoerper, FGFR5 antikoerper, FGFR5beta antikoerper, FGFR5gamma antikoerper, Fgfr5 antikoerper, FHFR antikoerper, XFGFRL1 antikoerper, Xndk antikoerper, fgfrl1-a antikoerper, fgfrl1-b antikoerper, ndk antikoerper, im:7154242 antikoerper, fibroblast growth factor receptor like 1a antikoerper, fibroblast growth factor receptor-like 1 antikoerper, fibroblast growth factor receptor like 1 antikoerper, fibroblast growth factor receptor like 1 L homeolog antikoerper, fibroblast growth factor receptor like 1b antikoerper, fgfrl1a antikoerper, Fgfrl1 antikoerper, FGFRL1 antikoerper, fgfrl1.L antikoerper, fgfrl1b antikoerper

Hintergrund: The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Molekulargewicht: 55 kDa

Gen-ID: 53834

UniProt: Q8N441

Pathways: RTK Signalweg