PRKAA2 Antikörper (Thr172)
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- Target Alle PRKAA2 Antikörper anzeigen
- PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
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Bindungsspezifität
- AA 145-173, Thr172
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PRKAA2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This PRKAA2 (Thr172) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-173 amino acids from the Central region of human PRKAA2 (Thr172).
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product PRKAA2 Primärantikörper
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- Applikationshinweise
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For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.45 mg/mL
- Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))
- Andere Bezeichnung
- PRKAA2 (PRKAA2 Produkte)
- Synonyme
- AMPK antikoerper, AMPK2 antikoerper, AMPKa2 antikoerper, PRKAA antikoerper, Ampk antikoerper, Ampka2 antikoerper, 2310008I11Rik antikoerper, A830082D05 antikoerper, AMPKalpha2 antikoerper, AMPKA2 antikoerper, ampk antikoerper, ampk2 antikoerper, prkaa antikoerper, prkaa1 antikoerper, PRKAA2 antikoerper, protein kinase AMP-activated catalytic subunit alpha 2 antikoerper, protein kinase, AMP-activated, alpha 2 catalytic subunit antikoerper, protein kinase, AMP-activated, alpha 2 catalytic subunit S homeolog antikoerper, PRKAA2 antikoerper, Prkaa2 antikoerper, prkaa2.S antikoerper, prkaa2 antikoerper
- Hintergrund
- The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
- Molekulargewicht
- 62 kDa
- Gen-ID
- 5563
- UniProt
- P54646
- Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, Warburg Effekt
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