KLKB1 Antikörper (C-Term)

Produktnummer ABIN5533087

Produktdetails anti-KLKB1 Antikörper

Target: KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))

Bindungsspezifität: AA 508-537, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLKB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This KLKB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-537 amino acids from the C-terminal region of human KLKB1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: For WB starting dilution is: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.47 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu KLKB1

Target: KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))

Andere Bezeichnung: KLKB1 (KLKB1 Produkte)

Synonyme: KLK3 antikoerper, PPK antikoerper, APS antikoerper, Kal-3 antikoerper, Kal3 antikoerper, Klk3 antikoerper, PSA antikoerper, KALP15 antikoerper, Kalp1 antikoerper, KLKB1 antikoerper, DKFZp459J2015 antikoerper, klkb1 antikoerper, kallikrein B1 antikoerper, kallikrein B, plasma 1 antikoerper, plasma kallikrein antikoerper, Plasma kallikrein antikoerper, kallikrein B, plasma (Fletcher factor) 1 antikoerper, coagulation factor XI antikoerper, kallikrein B1 L homeolog antikoerper, KLKB1 antikoerper, Klkb1 antikoerper, CpipJ_CPIJ004042 antikoerper, CpipJ_CPIJ014955 antikoerper, CpipJ_CPIJ020108 antikoerper, VAA_02266 antikoerper, LOC100549617 antikoerper, klkb1 antikoerper, klkb1.L antikoerper

Hintergrund: Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.

Molekulargewicht: 71 kDa

Gen-ID: 3818

UniProt: P03952

Pathways: Komplementsystem, Brown Fat Cell Differentiation