This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This XPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-250 amino acids from the C-terminal region of human XPA.
XPA
Reaktivität: Human
WB, ELISA, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
XPA
(Xeroderma Pigmentosum, Complementation Group A (XPA))
CG6358 antikoerper, DhR14 antikoerper, DhXPA antikoerper, DmXPA antikoerper, Dmel\\CG6358 antikoerper, Dxpa antikoerper, EG:EG0007.8 antikoerper, XPAC antikoerper, XPA_DROME antikoerper, Xpa antikoerper, dmXPA antikoerper, dxpa antikoerper, XP1 antikoerper, AI573865 antikoerper, Xpac antikoerper, xpac antikoerper, xxpa antikoerper, Xeroderma pigmentosum group A-like antikoerper, XPA, DNA damage recognition and repair factor antikoerper, xeroderma pigmentosum, complementation group A antikoerper, xeroderma pigmentosum, complementation group A L homeolog antikoerper, Xpac antikoerper, XPA antikoerper, Xpa antikoerper, xpa.L antikoerper
Hintergrund
XPA is involved in DNA excision repair. It initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. This protein is required for UV-induced CHK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.