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XPA Produkte

(Xeroderma Pigmentosum, Complementation Group A (XPA))

Kategorien

This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009].

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Ausgewählte XPA Kategorien

XPA Antikörper

High quality antibodies with extensive validation data.

XPA ELISA Kits

Reliable ELISA kits for a wide range of species.

XPA Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene XPA Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p), IP, ICC
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN2855566
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (4)
Kat. Nr. ABIN948624
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p), FACS
Validierungen
  • (3)
Kat. Nr. ABIN652730
Menge 400 μL
Datenblatt Datenblatt

Empfohlene XPA ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1381596
Menge 96 tests
Datenblatt Datenblatt

Empfohlene XPA Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1325438
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3075637
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7422931
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren XPA Produkten

Manandhar, Lowery, Boulware, Lin, Lu, Wood: "Transcriptional consequences of XPA disruption in human cell lines." in: DNA repair, Vol. 57, pp. 76-90, (2017) (PubMed).

Saquilabon Cruz, Kong, Silva, Khatibzadeh, Thai, Berns, Yokomori: "Femtosecond near-infrared laser microirradiation reveals a crucial role for PARP signaling on factor assemblies at DNA damage sites." in: Nucleic acids research, Vol. 44, Issue 3, pp. e27, (2016) (PubMed).

ODowd, Zavala, Brown, Mori, Fortunato: "HCMV-infected cells maintain efficient nucleotide excision repair of the viral genome while abrogating repair of the host genome." in: PLoS pathogens, Vol. 8, Issue 11, pp. e1003038, (2012) (PubMed).

Saijo, Matsuda, Kuraoka, Tanaka: "Inhibition of nucleotide excision repair by anti-XPA monoclonal antibodies which interfere with binding to RPA, ERCC1, and TFIIH." in: Biochemical and biophysical research communications, Vol. 321, Issue 4, pp. 815-22, (2004) (PubMed).

Araújo, Nigg, Wood: "Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosome." in: Molecular and cellular biology, Vol. 21, Issue 7, pp. 2281-91, (2001) (PubMed).

Evans, Fellows, Coffer, Wood: "Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein." in: The EMBO journal, Vol. 16, Issue 3, pp. 625-38, (1997) (PubMed).

Aboussekhra, Biggerstaff, Shivji, Vilpo, Moncollin, Podust, Protić, Hübscher, Egly, Wood: "Mammalian DNA nucleotide excision repair reconstituted with purified protein components." in: Cell, Vol. 80, Issue 6, pp. 859-68, (1995) (PubMed).

Tanaka, Miura, Satokata, Miyamoto, Yoshida, Satoh, Kondo, Yasui, Okayama, Okada: "Analysis of a human DNA excision repair gene involved in group A xeroderma pigmentosum and containing a zinc-finger domain." in: Nature, Vol. 348, Issue 6296, pp. 73-6, (1990) (PubMed).

Synonyme und alternative Namen zu XPA

Xeroderma pigmentosum group A-like (Xpac), XPA, DNA damage recognition and repair factor (XPA), xeroderma pigmentosum, complementation group A (Xpa), XPA, DNA damage recognition and repair factor (Xpa), xeroderma pigmentosum, complementation group A L homeolog (xpa.L), AI573865, CG6358, DhR14, DhXPA, Dmel\\CG6358, DmXPA, dmXPA, Dxpa, dxpa, EG:EG0007.8, XP1, Xpa, XPAC, Xpac, xpac, XPA_DROME, xxpa

Bezeichner auf Proteinebene für XPA

  • CG6358-PA
  • Xpac-PA
  • xeroderma pigmentosum group A-like
  • DNA repair protein complementing XP-A cells
  • excision repair-controlling
  • xeroderma pigmentosum group A-complementing protein
  • DNA repair protein complementing XP-A cells homolog
  • xeroderma pigmentosum group A-complementing protein homolog
  • xpacch protein
  • xpacx1 protein
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