XIAP Produkte
(X-Linked Inhibitor of Apoptosis (XIAP))
Kategorien
This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011].
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Ausgewählte XIAP Kategorien
XIAP Antikörper
High quality antibodies with extensive validation data.
XIAP ELISA Kits
Reliable ELISA kits for a wide range of species.
XIAP Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene XIAP Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p), ICC
Validierungen
- (5)
Kat. Nr.
ABIN2854771
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (5)
Kat. Nr.
ABIN6256441
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validierungen
- (4)
- (3)
Kat. Nr.
ABIN674364
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene XIAP ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6960570
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6971208
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN625470
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene XIAP Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125749
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1325435
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3096409
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren XIAP Produkten
: "Distinctive expression signatures of serum microRNAs in ischaemic stroke and transient ischaemic attack patients." in: Thrombosis and haemostasis, Vol. 117, Issue 5, pp. 992-1001, (2018) (PubMed).: "Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling." in: Journal of cell science, Vol. 131, Issue 10, (2018) (PubMed).
: "Low-level light emitting diode (LED) therapy suppresses inflammasome-mediated brain damage in experimental ischemic stroke." in: Journal of biophotonics, (2017) (PubMed).
: "Protective Effects of Fucoidan on Aβ25-35 and d-Gal-Induced Neurotoxicity in PC12 Cells and d-Gal-Induced Cognitive Dysfunction in Mice." in: Marine drugs, Vol. 15, Issue 3, (2017) (PubMed).
: "Inactivation of BRCA2 in human cancer cells identifies a subset of tumors with enhanced sensitivity towards death receptor-mediated apoptosis." in: Oncotarget, Vol. 7, Issue 8, pp. 9477-90, (2017) (PubMed).
: "Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer." in: Journal of bioenergetics and biomembranes, (2015) (PubMed).
: "Gene transfection mediated by polyethyleneimine-polyethylene glycol nanocarrier prevents cisplatin-induced spiral ganglion cell damage." in: Neural regeneration research, Vol. 10, Issue 3, pp. 425-31, (2015) (PubMed).
: "Smac mimetic?induced caspase?independent necroptosis requires RIP1 in breast cancer." in: Molecular medicine reports, (2015) (PubMed).
: "Ampelopsin induces apoptosis by regulating multiple c?Myc/S?phase kinase?associated protein 2/F?box and WD repeat?containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma ..." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 105-12, (2014) (PubMed).
: "Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7? and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549." in: PLoS ONE, Vol. 8, Issue 11, pp. e79201, (2013) (PubMed).
Synonyme und alternative Namen zu XIAP
X-linked inhibitor of apoptosis (XIAP), X-linked inhibitor of apoptosis (xiap), X-linked inhibitor of apoptosis L homeolog (xiap.L), X-linked inhibitor of apoptosis (Xiap), 1110015C02Rik, Aipa, API3, api3, Api3, BIRC4, birc4, Birc4, BIRC8, fb73d01, hIAP-3, hIAP3, IAP-3, IAP3, ILP-1, ILP1, ilp1, MIHA, miha, mXIAP, riap3, wu:fb73d01, XLP2, xlp2, xxiap, zgc:91873Bezeichner auf Proteinebene für XIAP
- E3 ubiquitin-protein ligase XIAP
- IAP-like protein
- X-linked IAP
- baculoviral IAP repeat-containing protein 4
- inhibitor of apoptosis protein 3
- Baculoviral IAP repeat-containing protein 4
- X-linked inhibitor of apoptosis protein
- baculoviral IAP repeat-containing 4
- baculoviral IAP-repeat containing protein 4
- IAP homolog A
- IAP-3
- apoptosis inhibitor 3
- mIAP-3
- mIAP3
- RIAP-3
- apoptosis inhibitor protein 3
- baculoviral IAP repeat containing 8
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