XAF1 Produkte
(XiAP Associated Factor 1 (XAF1))
Kategorien
This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].
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Ausgewählte XAF1 Kategorien
XAF1 Antikörper
High quality antibodies with extensive validation data.
XAF1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene XAF1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse, Rat
Applikation
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
- (3)
Kat. Nr.
ABIN674754
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (3)
Kat. Nr.
ABIN527175
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC (p)
Validierungen
- (2)
- (2)
Kat. Nr.
ABIN540591
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene XAF1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6971212
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene XAF1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125752
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1325416
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1325418
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren XAF1 Produkten
: "SARM1 deficiency up-regulates XAF1, promotes neuronal apoptosis, and accelerates prion disease." in: The Journal of experimental medicine, Vol. 216, Issue 4, pp. 743-756, (2019) (PubMed).: "Admixture fine-mapping in African Americans implicates XAF1 as a possible sarcoidosis risk gene." in: PLoS ONE, Vol. 9, Issue 3, pp. e92646, (2014) (PubMed).
: "A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer." in: Nature genetics, Vol. 45, Issue 7, pp. 747-55, (2013) (PubMed).
: "Combination of DNA methylation inhibitor 5-azacytidine and arsenic trioxide has synergistic activity in myeloma." in: European journal of haematology, Vol. 82, Issue 3, pp. 176-83, (2009) (PubMed).
: "Down-regulation of the pro-apoptotic XIAP associated factor-1 (XAF1) during progression of clear-cell renal cancer." in: BMC cancer, Vol. 9, pp. 276, (2009) (PubMed).
: "Wild-type PABPN1 is anti-apoptotic and reduces toxicity of the oculopharyngeal muscular dystrophy mutation." in: Human molecular genetics, Vol. 17, Issue 8, pp. 1097-108, (2008) (PubMed).
: "XAF1 mediates tumor necrosis factor-alpha-induced apoptosis and X-linked inhibitor of apoptosis cleavage by acting through the mitochondrial pathway." in: The Journal of biological chemistry, Vol. 282, Issue 17, pp. 13059-72, (2007) (PubMed).
: "Xaf1 can cooperate with TNFalpha in the induction of apoptosis, independently of interaction with XIAP." in: Molecular and cellular biochemistry, Vol. 286, Issue 1-2, pp. 67-76, (2006) (PubMed).
: "The Bcl-2 protein family and its role in the development of neoplastic disease." in: Experimental gerontology, Vol. 39, Issue 8, pp. 1125-35, (2004) (PubMed).
: "X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia-ischemia." in: Neurobiology of disease, Vol. 16, Issue 1, pp. 179-89, (2004) (PubMed).
Synonyme und alternative Namen zu XAF1
XIAP associated factor 1 (xaf1), XIAP associated factor 1 (XAF1), XIAP associated factor 1 (Xaf1), BIRC4BP, Fbxo39, HSXIAPAF1, XIAPAF1Bezeichner auf Proteinebene für XAF1
- XIAP-associated factor 1
- BIRC4 binding protein
- BIRC4-binding protein
- F-box protein 39
- novel TRAF-type zinc finger protein
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