XIAP Antikörper (AA 1-268)

Produktnummer ABIN7193408

Produktdetails anti-XIAP Antikörper

Target: XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

Bindungsspezifität: AA 1-268

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser XIAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human XIAP (AA: 1-268) expressed in E. coli.

Klon: 4C12G10

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: WB:1:500 - 1:2000, FCM:1:200 - 1:400, ELISA:1:10000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu XIAP

Target: XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

Andere Bezeichnung: XIAP (XIAP Produkte)

Synonyme: API3 antikoerper, BIRC4 antikoerper, IAP-3 antikoerper, ILP1 antikoerper, MIHA antikoerper, XLP2 antikoerper, hIAP-3 antikoerper, hIAP3 antikoerper, api3 antikoerper, birc4 antikoerper, ilp1 antikoerper, miha antikoerper, xlp2 antikoerper, xxiap antikoerper, 1110015C02Rik antikoerper, Aipa antikoerper, Api3 antikoerper, Birc4 antikoerper, IAP3 antikoerper, ILP-1 antikoerper, mXIAP antikoerper, riap3 antikoerper, fb73d01 antikoerper, wu:fb73d01 antikoerper, zgc:91873 antikoerper, BIRC8 antikoerper, X-linked inhibitor of apoptosis antikoerper, X-linked inhibitor of apoptosis L homeolog antikoerper, XIAP antikoerper, xiap antikoerper, xiap.L antikoerper, Xiap antikoerper

Hintergrund:

Description: This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]

Aliases: API3, ILP1, MIHA, XLP2, BIRC4, IAP-3, hIAP3, hIAP-3

Molekulargewicht: 56.7 kDa

Gen-ID: 331

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Transition Metal Ion Homeostasis