XIAP Antikörper (N-Term)

Produktnummer ABIN390070

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch XIAP in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für XIAP Antikörper (N-Term) (ABIN390070)

Target: XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XIAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB01793

Produktdetails anti-XIAP Antikörper

Bindungsspezifität: AA 1-30, N-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This XIAP (BIRC4) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human XIAP (BIRC4).

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu XIAP

Target: XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

Andere Bezeichnung: XIAP (BIRC4)

Hintergrund: BIRC4 is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. Similar to API1, BIRC4 inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. BIRC4 also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.

Molekulargewicht: 56685

Gen-ID: 331

NCBI Accession: NP_001158, NP_001191330

UniProt: P98170

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Transition Metal Ion Homeostasis