RAD51 Homolog B Antikörper (Middle Region)

Produktnummer ABIN5517302

Produktdetails anti-RAD51 Homolog B Antikörper

Target: RAD51 Homolog B (Rad51B)

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD51 Homolog B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EFDAQLQGNL KERNKFLARE ASSLKYLAEE FSIPVILTNQ ITTHLSGALA

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RAD51B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RAD51 Homolog B

Target: RAD51 Homolog B (Rad51B)

Andere Bezeichnung: RAD51B (Rad51B Produkte)

Synonyme: R51H2 antikoerper, RAD51L1 antikoerper, REC2 antikoerper, AI553500 antikoerper, Rad51l1 antikoerper, mREC2 antikoerper, ATRAD51B antikoerper, T17D12.12 antikoerper, T17D12_12 antikoerper, RGD1560681 antikoerper, rad51l1 antikoerper, wu:fd07f04 antikoerper, zgc:56581 antikoerper, RAD51 paralog B antikoerper, DNA repair (Rad51) family protein antikoerper, Rad51 DNA recombinase 2 antikoerper, RAD51B antikoerper, Rad51b antikoerper, rad51b antikoerper

Hintergrund: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.

Alias Symbols: REC2, R51H2, RAD51L1

Protein Size: 279

Gen-ID: 5890

NCBI Accession: NP_002868

Pathways: DNA Reparatur