RAD51 Homolog B Antikörper (Middle Region)

Produktnummer ABIN2787357

Produktdetails anti-RAD51 Homolog B Antikörper

Target: RAD51 Homolog B (Rad51B)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD51 Homolog B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TESAFSAERL VEIAESRFPR YFNTEEKLLL TSSKVHLYRE LTCDEVLQRI

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against RAD51L1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RAD51L1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 350 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RAD51 Homolog B

Target: RAD51 Homolog B (Rad51B)

Andere Bezeichnung: RAD51L1 (Rad51B Produkte)

Synonyme: R51H2 antikoerper, RAD51L1 antikoerper, REC2 antikoerper, AI553500 antikoerper, Rad51l1 antikoerper, mREC2 antikoerper, ATRAD51B antikoerper, T17D12.12 antikoerper, T17D12_12 antikoerper, RGD1560681 antikoerper, rad51l1 antikoerper, wu:fd07f04 antikoerper, zgc:56581 antikoerper, RAD51 paralog B antikoerper, DNA repair (Rad51) family protein antikoerper, Rad51 DNA recombinase 2 antikoerper, RAD51B antikoerper, Rad51b antikoerper, rad51b antikoerper

Hintergrund: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: MGC34245, R51H2, RAD51B, REC2, hREC2, RAD51L1
Protein Interaction Partner: FAM9B, SWSAP1, UBC, HIST1H2BG, HIST2H4A, RAD51D, HIST1H3A, RAD51C, H1F0, XRCC2, RAD51, HIST1H1A, HIST3H2BB, HIST3H3, HIST4H4,
Protein Size: 350

Molekulargewicht: 38 kDa

Gen-ID: 5890

NCBI Accession: NM_133510, NP_598194

Pathways: DNA Reparatur