RAD51 Homolog B Antikörper (AA 201-250)

Produktnummer ABIN1534486

Der Kaninchen Polyklonal anti-RAD51 Homolog B Antikörper wird verwendet zum Nachweis von RAD51 Homolog B in Proben von Human, Maus und Affe. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für RAD51 Homolog B Antikörper (AA 201-250) (ABIN1534486)

Target: RAD51 Homolog B (Rad51B)

Reaktivität: Human, Maus, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD51 Homolog B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-RAD51 Homolog B Antikörper

Bindungsspezifität: AA 201-250

Verwendungszweck: Rad51B Antibody

Spezifität: Rad51B Polyclonal Antibody detects endogenous levels of Rad51B protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human RAD51L1. AA range:201-250

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu RAD51 Homolog B

Target: RAD51 Homolog B (Rad51B)

Andere Bezeichnung: RAD51L1

Hintergrund:

Synonyms: RAD51B, RAD51L1, REC2, DNA repair protein RAD51 homolog 2, R51H2, RAD51 homolog B, Rad51B, RAD51-like protein 1

Background: RAD51 paralog B(RAD51B) Homo sapiens The protein encoded byThis gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Mar 2016],

Gene Name: RAD51B

Protein Name: DNA repair protein RAD51 homolog 2

Molekulargewicht: 42 kDa

Gen-ID: 5890

OMIM: 150699

UniProt: O15315

Pathways: DNA Reparatur