AKR1C1 Antikörper (Middle Region)

Produktnummer ABIN5515960

Produktdetails anti-AKR1C1 Antikörper

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKR1C1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KIADGSVKRE DIFYTSKLWC NSHRPELVRP ALERSLKNLQ LDYVDLYLIH

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AKR1C1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AKR1C1

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Andere Bezeichnung: AKR1C1 (DDH Produkte)

Synonyme: 2-ALPHA-HSD antikoerper, 20-ALPHA-HSD antikoerper, C9 antikoerper, DD1 antikoerper, DD1/DD2 antikoerper, DDH antikoerper, DDH1 antikoerper, H-37 antikoerper, HAKRC antikoerper, HBAB antikoerper, MBAB antikoerper, aldo-keto reductase family 1 member C1 antikoerper, aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) antikoerper, AKR1C1 antikoerper

Hintergrund: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Alias Symbols: C9, DD1, DDH, DDH1, H-37, HBAB, MBAB, HAKRC, DD1/DD2, 2-ALPHA-HSD, 20-ALPHA-HSD

Protein Size: 323

Gen-ID: 1645

NCBI Accession: NP_001344

UniProt: Q04828

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process