AKR1C1 Antikörper (AA 1-323)

Produktnummer ABIN6136721

Produktdetails anti-AKR1C1 Antikörper

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Bindungsspezifität: AA 1-323

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKR1C1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MDSKYQCVKL NDGHFMPVLG FGTYAPAEVP KSKALEATKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWCNSH RPELVRPALE RSLKNLQLDY VDLYLIHFPV SVKPGEEVIP KDENGKILFD TVDLCATWEA VEKCKDAGLA KSIGVSNFNR RQLEMILNKP GLKYKPVCNQ VECHPYFNQR KLLDFCKSKD IVLVAYSALG SHREEPWVDP NSPVLLEDPV LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIRQN VQVFEFQLTS EEMKAIDGLN RNVRYLTLDI FAGPPNYPFS DEY

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human AKR1C1 (NP_001344.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:3000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu AKR1C1

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Andere Bezeichnung: AKR1C1 (DDH Produkte)

Synonyme: 2-ALPHA-HSD antikoerper, 20-ALPHA-HSD antikoerper, C9 antikoerper, DD1 antikoerper, DD1/DD2 antikoerper, DDH antikoerper, DDH1 antikoerper, H-37 antikoerper, HAKRC antikoerper, HBAB antikoerper, MBAB antikoerper, aldo-keto reductase family 1 member C1 antikoerper, aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) antikoerper, AKR1C1 antikoerper

Hintergrund: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.,AKR1C1,2-ALPHA-HSD,20-ALPHA-HSD,C9,DD1,DD1/DD2,DDH,DDH1,H-37,HAKRC,HBAB,MBAB,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Drug metabolism,AKR1C1

Molekulargewicht: 36 kDa

Gen-ID: 1645

UniProt: Q04828

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process