AKR1C1 Antikörper (AA 1-323)

Produktnummer ABIN5776092

Dieser Maus Monoklonal Antikörper detektiert spezifisch AKR1C1 in WB, ELISA, IF, ICC und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für AKR1C1 Antikörper (AA 1-323) (ABIN5776092)

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser AKR1C1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Klon: AT6D10

Produktdetails anti-AKR1C1 Antikörper

Bindungsspezifität: AA 1-323

Verwendungszweck: Human Aldo-keto Reductase 1C1/AKR1C1 antibody

Aufreinigung: Purified

Immunogen: Recombinant human AKR1C1 (1-323aa) purified from E. coli

Isotyp: IgG1 kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Details zu AKR1C1

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Andere Bezeichnung: Aldo-keto Reductase 1C1/AKR1C1

Hintergrund: The human aldo-keto reductases 1C1 and 1C3 (AKR1C1 and AKR1C3) have major roles in pre receptor regulation of progesterone action. They can both convert progesterone to the less potent efficiencies. AKR1C1 and AKR1C3 also act as 3-ketosteroid reductase, and as such they can convert the most potent androgen 5alpha-DHT into 3beta-andorstandiol, which is an estrogen receptor beta ligand, and into the inactive androgen 3alpha-androstnionl, respectively.

NCBI Accession: NP_001344

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process