AKR1C1 Antikörper (AA 1-323)

Produktnummer ABIN514921

Produktdetails anti-AKR1C1 Antikörper

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Bindungsspezifität: AA 1-323

Reaktivität: Human

Wirt: Maus

Klonalität: Polyklonal

Konjugat: Dieser AKR1C1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Mouse polyclonal antibody raised against a full-length human AKR1C1 protein.

Sequenz: MDSKYQCVKL NDGHFMPVLG FGTYAPAEVP KSKALEATKL AIEAGFRHID SAHLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWCNSH RPELVRPALE RSLKNLQLDY VDLYLIHFPV SVKPGEEVIP KDENGKILFD TVDLCATWEA VEKCKDAGLA KSIGVSNFNR RQLEMILNKP GLKYKPVCNQ VECHPYFNQR KLLDFCKSKD IVLVAYSALG SHREEPWVDP NSPVLLEDPV LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIRQN VQVFEFQLTS EEMKAIDGLN RNVRYLTLDI FAGPPNYPFS DEY

Kreuzreaktivität: Human

Produktmerkmale: Antibody reactive against mammalian transfected lysate.

Immunogen: AKR1C1 (NP_001344.2, 1 a.a. ~ 323 a.a) full-length human protein.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-AKR1C1 Antikörper (ABIN514921)

Han, Bourboulia, Jensen-Taubman, Isaac, Wei, Stetler-Stevenson: "An endogenous inhibitor of angiogenesis inversely correlates with side population phenotype and function in human lung cancer cells." in: Oncogene, Vol. 33, Issue 9, pp. 1198-206, (2014) (PubMed).

Choi, Ryoo, Kang, Kwak: "The sensitivity of cancer cells to pheophorbide a-based photodynamic therapy is enhanced by Nrf2 silencing." in: PLoS ONE, Vol. 9, Issue 9, pp. e107158, (2014) (PubMed).

Ebert, Kisiela, Wsól, Maser: "Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29." in: Chemico-biological interactions, Vol. 191, Issue 1-3, pp. 239-49, (2011) (PubMed).

Details zu AKR1C1

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Andere Bezeichnung: AKR1C1 (DDH Produkte)

Synonyme: 2-ALPHA-HSD antikoerper, 20-ALPHA-HSD antikoerper, C9 antikoerper, DD1 antikoerper, DD1/DD2 antikoerper, DDH antikoerper, DDH1 antikoerper, H-37 antikoerper, HAKRC antikoerper, HBAB antikoerper, MBAB antikoerper, aldo-keto reductase family 1 member C1 antikoerper, aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) antikoerper, AKR1C1 antikoerper

Hintergrund: Full Gene Name: aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1, 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
Synonyms: 2-ALPHA-HSD,20-ALPHA-HSD,C9,DD1,DDH,DDH1,H-37,HAKRC,MBAB,MGC8954

Gen-ID: 1645

NCBI Accession: NM_001353

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process