ABL1 Antikörper (pTyr245)

Produktnummer ABIN548465

Produktdetails anti-ABL1 Antikörper

Target: ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))

Bindungsspezifität: pTyr245

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic phosphopeptide of ABL1.

Spezifität: This peptide sequence has high homology to the conserved site in rat and mouse c-Abl, as well as in viral Abl and BCR-Abl fusion protein.

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Antibody Reactive Against Synthetic Peptide.

Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y245 of human ABL1.

Anwendungsinformationen

Applikationshinweise: ELISA (1:2000)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (50 % glycerol, 1 mg/mL BSA, 0.05 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-ABL1 Antikörper (ABIN548465)

Pluk, Dorey, Superti-Furga: "Autoinhibition of c-Abl." in: Cell, Vol. 108, Issue 2, pp. 247-59, (2002) (PubMed).

Brasher, Van Etten: "c-Abl has high intrinsic tyrosine kinase activity that is stimulated by mutation of the Src homology 3 domain and by autophosphorylation at two distinct regulatory tyrosines." in: The Journal of biological chemistry, Vol. 275, Issue 45, pp. 35631-7, (2000) (PubMed).

Details zu ABL1

Target: ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))

Andere Bezeichnung: ABL1 (ABL1 Produkte)

Synonyme: ABL antikoerper, JTK7 antikoerper, bcr/abl antikoerper, c-ABL antikoerper, p150 antikoerper, v-abl antikoerper, AI325092 antikoerper, Abl antikoerper, E430008G22Rik antikoerper, c-Abl antikoerper, ABL proto-oncogene 1, non-receptor tyrosine kinase antikoerper, c-abl oncogene 1, non-receptor tyrosine kinase antikoerper, Tyrosine-protein kinase abl-1 antikoerper, ABL1 antikoerper, Abl1 antikoerper, abl-1 antikoerper, abl1 antikoerper

Gen-ID: 25

Pathways: Apoptose, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism