ATG5 Antikörper (AA 1-50)

Produktnummer ABIN540779

Produktdetails anti-ATG5 Antikörper

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Bindungsspezifität: AA 1-50

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Schwein, Xenopus laevis, Primate

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic peptide of ATG5.

Spezifität: This antibody is selective for the full-length and calpain cleaved isoform proteins. The short isoform is missing a.a. 1-79. The calpain cleaved form of ATG5 is missing a.a. 195-275.

Kreuzreaktivität: Rind (Kuh), Human, Maus, Schwein, Primate, Ratte, Xenopus laevis, Zebrafisch (Danio rerio)

Immunogen: A synthetic peptide corresponding to amino acids 1-50 of human ATG5.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.5 μg/mL)
Western Blot (1:500)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (30 % glycerol, 0.09 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-ATG5 Antikörper (ABIN540779)

Wang, Singh, Massey, Kane, Kaushik, Grant, Xiang, Cuervo, Czaja: "Loss of macroautophagy promotes or prevents fibroblast apoptosis depending on the death stimulus." in: The Journal of biological chemistry, Vol. 283, Issue 8, pp. 4766-77, (2008) (PubMed).

Pyo, Nah, Kim, Lee, Heo, Lee, Jung: "Compensatory activation of ERK1/2 in Atg5-deficient mouse embryo fibroblasts suppresses oxidative stress-induced cell death." in: Autophagy, Vol. 4, Issue 3, pp. 315-21, (2008) (PubMed).

Cadwell, Liu, Brown, Miyoshi, Loh, Lennerz, Kishi, Kc, Carrero, Hunt, Stone, Brunt, Xavier, Sleckman, Li, Mizushima, Stappenbeck, Virgin: "A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells." in: Nature, Vol. 456, Issue 7219, pp. 259-63, (2008) (PubMed).

Details zu ATG5

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Andere Bezeichnung: APG5L / ATG5 (ATG5 Produkte)

Synonyme: APG5 antikoerper, APG5-LIKE antikoerper, APG5L antikoerper, ASP antikoerper, hAPG5 antikoerper, ATG5 antikoerper, CG1643 antikoerper, DmAtg5 antikoerper, Dmel\\CG1643 antikoerper, atg5 antikoerper, 2010107M05Rik antikoerper, 3110067M24Rik antikoerper, AW319544 antikoerper, Apg5l antikoerper, Atg5l antikoerper, C88337 antikoerper, Paddy antikoerper, apg5l antikoerper, zgc:100934 antikoerper, ATATG5 antikoerper, AUTOPHAGY 5 antikoerper, MKP11.20 antikoerper, MKP11_20 antikoerper, autophagy related 5 antikoerper, Autophagy-related 5 antikoerper, ATG5 autophagy related 5 homolog (S. cerevisiae) antikoerper, autophagy related 5 L homeolog antikoerper, similar to S. cerevisiae ATG5 (YPL149W) which nucleates preautophagosome formation as a conjugate with Atg12 antikoerper, autophagy protein Apg5 family antikoerper, ATG5 antikoerper, Atg5 antikoerper, atg5 antikoerper, atg5.L antikoerper, APG5 antikoerper

Gen-ID: 9474

Pathways: Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagie