DcR1 Antikörper (AA 1-280) (FITC)

Produktnummer ABIN536702

Produktdetails anti-DcR1 Antikörper (FITC)

Target: DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

Bindungsspezifität: AA 1-280

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DcR1 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Verwendungszweck: Mouse monoclonal antibody raised against recombinant TNFRSF10C.

Spezifität: This antibody reacts with TRAIL-R3, a 35 KDa GPI-anchored extracellular membrane protein expressed mainly on neutrophils.

Kreuzreaktivität: Human

Immunogen: Recombinant Fc fusion protein corresponding to amino acids 1-280 of TNFRSF10C.

Klon: TRAIL-R3-02

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry (3 μg/mL)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: In PBS (0.2 % BSA, 0.09 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-DcR1 Antikörper (FITC) (ABIN536702)

Mérino, Lalaoui, Morizot, Schneider, Solary, Micheau: "Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2." in: Molecular and cellular biology, Vol. 26, Issue 19, pp. 7046-55, (2006) (PubMed).

Sanlioglu, Dirice, Aydin, Erin, Koksoy, Sanlioglu: "Surface TRAIL decoy receptor-4 expression is correlated with TRAIL resistance in MCF7 breast cancer cells." in: BMC cancer, Vol. 5, pp. 54, (2005) (PubMed).

Clancy, Mruk, Archer, Woelfel, Mongkolsapaya, Screaton, Lenardo, Chan: "Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 50, pp. 18099-104, (2005) (PubMed).

Details zu DcR1

Target: DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

Andere Bezeichnung: CD263 / TRAILR3 (TNFRSF10C Produkte)

Synonyme: CD263 antikoerper, DCR1 antikoerper, DCR1-TNFR antikoerper, LIT antikoerper, TRAIL-R3 antikoerper, TRAILR3 antikoerper, TRID antikoerper, TNFRSF10C antikoerper, TNF receptor superfamily member 10c antikoerper, TNFRSF10C antikoerper

Gen-ID: 8794

Pathways: Apoptose