DcR1 Antikörper (AA 30-130)

Produktnummer ABIN3021518

Produktdetails anti-DcR1 Antikörper

Target: DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

Bindungsspezifität: AA 30-130

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DcR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RQEEVPQQTV APQQQRHSFK GEECPAGSHR SEHTGACNPC TEGVDYTNAS NNEPSCFPCT VCKSDQKHKS SCTMTRDTVC QCKEGTFRNE NSPEMCRKCS R

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-130 of human TNFRSF10C (NP_003832.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DcR1

Target: DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

Andere Bezeichnung: TNFRSF10C (TNFRSF10C Produkte)

Synonyme: CD263 antikoerper, DCR1 antikoerper, DCR1-TNFR antikoerper, LIT antikoerper, TRAIL-R3 antikoerper, TRAILR3 antikoerper, TRID antikoerper, TNFRSF10C antikoerper, TNF receptor superfamily member 10c antikoerper, TNFRSF10C antikoerper

Hintergrund: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.,TNFRSF10C,CD263,DCR1,DCR1-TNFR,LIT,TRAIL-R3,TRAILR3,TRID,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,CD markers,Cytokines,NF-kB Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TNFRSF10C

Molekulargewicht: 27 kDa

Gen-ID: 8794

UniProt: O14798

Pathways: Apoptose