DcR1 Produkte
(Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
Kategorien
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008].
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Ausgewählte DcR1 Kategorien
DcR1 Antikörper
High quality antibodies with extensive validation data.
DcR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
DcR1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene DcR1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
FACS
Validierungen
- (3)
Kat. Nr.
ABIN301991
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human, Rat
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN6265636
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
FACS
Validierungen
- (2)
Kat. Nr.
ABIN6579816
Menge
0.1 mg
Datenblatt
Datenblatt
Empfohlene DcR1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6960280
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN5510573
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN1117673
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene DcR1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7275773
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1323146
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
- (1)
Kat. Nr.
ABIN3074721
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren DcR1 Produkten
: "Impact of p53 status on TRAIL-mediated apoptotic and non-apoptotic signaling in cancer cells." in: PLoS ONE, Vol. 14, Issue 4, pp. e0214847, (2019) (PubMed).: "Combination therapy with c-met inhibitor and TRAIL enhances apoptosis in dedifferentiated liposarcoma patient-derived cells." in: BMC cancer, Vol. 19, Issue 1, pp. 496, (2019) (PubMed).
: "TRAIL-Receptor 4 Modulates γδ T Cell-Cytotoxicity Toward Cancer Cells." in: Frontiers in immunology, Vol. 10, pp. 2044, (2019) (PubMed).
: "Dual role of DR5 in death and survival signaling leads to TRAIL resistance in cancer cells." in: Cell death & disease, Vol. 8, Issue 8, pp. e3025, (2018) (PubMed).
: "TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis." in: Scientific reports, Vol. 7, Issue 1, pp. 5514, (2017) (PubMed).
: "Targeting Apoptotic Activity Against Prostate Cancer Stem Cells." in: International journal of molecular sciences, Vol. 18, Issue 8, (2017) (PubMed).
: "The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2." in: Molecular cell, Vol. 65, Issue 4, pp. 730-742.e5, (2017) (PubMed).
: "Potential application of temozolomide in mesenchymal stem cell-based TRAIL gene therapy against malignant glioma." in: Stem cells translational medicine, Vol. 3, Issue 2, pp. 172-82, (2014) (PubMed).
: "Dominant negative effects of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 4 on TRAIL receptor 1 signaling by formation of heteromeric complexes." in: The Journal of biological chemistry, Vol. 289, Issue 23, pp. 16576-87, (2014) (PubMed).
: "TRAIL-engineered bone marrow-derived mesenchymal stem cells: TRAIL expression and cytotoxic effects on C6 glioma cells." in: Anticancer research, Vol. 34, Issue 2, pp. 729-34, (2014) (PubMed).
Synonyme und alternative Namen zu DcR1
TNF receptor superfamily member 10c (TNFRSF10C), CD263, DCR1, DCR1-TNFR, LIT, TNFRSF10C, TRAIL-R3, TRAILR3, TRIDBezeichner auf Proteinebene für DcR1
- TNF-related apoptosis-inducing ligand receptor 3
- antagonist decoy receptor for TRAIL/Apo-2L
- cytotoxic TRAIL receptor-3
- decoy TRAIL receptor without death domain
- decoy receptor 1
- lymphocyte inhibitor of TRAIL
- tumor necrosis factor receptor superfamily member 10C
- tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
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