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DCK Produkte

(Deoxycytidine Kinase (DCK))

Kategorien

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008].

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Ausgewählte DCK Kategorien

DCK Antikörper

High quality antibodies with extensive validation data.

DCK ELISA Kits

Reliable ELISA kits for a wide range of species.

DCK Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene DCK Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IF, IP, IHC (p), ICC
Validierungen
  • (6)
Kat. Nr. ABIN2856517
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF, IP, IHC (p), ICC
Validierungen
  • (8)
Kat. Nr. ABIN2855484
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF, IHC (p), FACS
Validierungen
  • (7)
Kat. Nr. ABIN1497773
Menge 100 μL
Datenblatt Datenblatt

Empfohlene DCK ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966319
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955345
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN5593143
Menge 96 tests
Datenblatt Datenblatt

Empfohlene DCK Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122632
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1351188
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1351190
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren DCK Produkten

Freiburghaus, Emruli, Johansson, Eskelund, Grønbæk, Olsson, Ek, Jerkeman, Ek: "Bortezomib prevents cytarabine resistance in MCL, which is characterized by down-regulation of dCK and up-regulation of SPIB resulting in high NF-κB activity." in: BMC cancer, Vol. 18, Issue 1, pp. 466, (2018) (PubMed).

Elebro, Ben Dror, Heby, Nodin, Jirström, Eberhard: "Prognostic effect of hENT1, dCK and HuR expression by morphological type in periampullary adenocarcinoma, including pancreatic cancer." in: Acta oncologica (Stockholm, Sweden), Vol. 55, Issue 3, pp. 286-96, (2016) (PubMed).

Bieghs, Caers, De Bruyne, Van Valckenborgh, Higginbotham, Vanderkerken, Menu: "The effects of forodesine in murine and human multiple myeloma cells." in: Advances in hematology, Vol. 2010, pp. 131895, (2010) (PubMed).

Hartford, Duan, Delaney, Mi, Kistner, Lamba, Huang, Dolan: "Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity." in: Blood, Vol. 113, Issue 10, pp. 2145-53, (2009) (PubMed).

Costantino, Witkiewicz, Kuwano, Cozzitorto, Kennedy, Dasgupta, Keen, Yeo, Gorospe, Brody: "The role of HuR in gemcitabine efficacy in pancreatic cancer: HuR Up-regulates the expression of the gemcitabine metabolizing enzyme deoxycytidine kinase." in: Cancer research, Vol. 69, Issue 11, pp. 4567-72, (2009) (PubMed).

Funel, Giovannetti, Del Chiaro, Mey, Pollina, Nannizzi, Boggi, Ricciardi, Del Tacca, Bevilacqua, Mosca, Danesi, Campani: "Laser microdissection and primary cell cultures improve pharmacogenetic analysis in pancreatic adenocarcinoma." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 88, Issue 7, pp. 773-84, (2008) (PubMed).

Lamba, Crews, Pounds, Schuetz, Gresham, Gandhi, Plunkett, Rubnitz, Ribeiro: "Pharmacogenetics of deoxycytidine kinase: identification and characterization of novel genetic variants." in: The Journal of pharmacology and experimental therapeutics, Vol. 323, Issue 3, pp. 935-45, (2007) (PubMed).

Innoceta, Galluzzi, Ruzzo, Andreoni, Chiarantini, Magnani: "Molecular basis of 2',3'-dideoxycytidine-induced drug resistance in human cells." in: Molecular and cellular biochemistry, Vol. 231, Issue 1-2, pp. 173-7, (2002) (PubMed).

Synonyme und alternative Namen zu DCK

deoxycytidine kinase (DCK), deoxycytidine kinase (dck), deoxycytidine kinase, gene 2 L homeolog (dck.2.L), deoxycytidine kinase, gene 2 (dck.2), deoxycytidine kinase (Dck), Deoxycytidine kinase (FPV059), Deoxycytidine kinase (FPV151), deoxycytidine kinase, gene 1 L homeolog (dck.1.L), dck, DCK, dck1, wu:fc15f06, zgc:101771

Bezeichner auf Proteinebene für DCK

  • deoxynucleoside kinase
  • Deoxycytidine kinase
  • deoxycytidine kinase
  • deoxycytidine kinase 1
  • deoxyribonucleoside kinase
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