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SHP1 Antikörper (C-Term)

PTPN6 Reaktivität: Human WB, ELISA, ICC, IP Wirt: Maus Monoclonal M160 unconjugated
Produktnummer ABIN533154
  • Target Alle SHP1 (PTPN6) Antikörper anzeigen
    SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
    Bindungsspezifität
    • 35
    • 12
    • 7
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 121
    • 75
    • 57
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 108
    • 15
    • 1
    Maus
    Klonalität
    • 96
    • 28
    Monoklonal
    Konjugat
    • 62
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser SHP1 Antikörper ist unkonjugiert
    Applikation
    • 87
    • 33
    • 27
    • 23
    • 22
    • 14
    • 14
    • 11
    • 10
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunoprecipitation (IP)
    Verwendungszweck
    Mouse monoclonal antibody raised against partial recombinant PTPN6.
    Spezifität
    This sequence is highly conserved in rat and mouse SHP1.
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    Recombinant protein corresponding to C-terminus of human PTPN6.
    Klon
    M160
    Isotyp
    IgG1
    Top Product
    Discover our top product PTPN6 Primärantikörper
  • Applikationshinweise
    ELISA (1:2000)
    Immunocytochemistry (1:100)
    Immunoprecipitation (5-10 µL)
    Western Blot (1:500)
    The optimal working dilution should be determined by the end user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In PBS (50 % glycerol, 1 mg/mL BSA, 0.05 % sodium azide)
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Jones, Craik, Gibbins, Poole: "Regulation of SHP-1 tyrosine phosphatase in human platelets by serine phosphorylation at its C terminus." in: The Journal of biological chemistry, Vol. 279, Issue 39, pp. 40475-83, (2004) (PubMed).

    Zhang, Shen, Lu, Cole: "The role of C-terminal tyrosine phosphorylation in the regulation of SHP-1 explored via expressed protein ligation." in: The Journal of biological chemistry, Vol. 278, Issue 7, pp. 4668-74, (2003) (PubMed).

    Zhang, Somani, Siminovitch: "Roles of the SHP-1 tyrosine phosphatase in the negative regulation of cell signalling." in: Seminars in immunology, Vol. 12, Issue 4, pp. 361-78, (2000) (PubMed).

  • Target
    SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
    Andere Bezeichnung
    PTPN6 (PTPN6 Produkte)
    Synonyme
    HCPH antikoerper, HPTP1C antikoerper, PTP-1C antikoerper, SH-PTP1 antikoerper, SHP-1 antikoerper, SHP-1L antikoerper, SHP1 antikoerper, DRPLA antikoerper, Hcph antikoerper, Ptp1C antikoerper, me antikoerper, motheaten antikoerper, Ptph6 antikoerper, Shp-1 antikoerper, fj22f05 antikoerper, wu:fj22f05 antikoerper, zgc:55501 antikoerper, ptpn6 antikoerper, protein tyrosine phosphatase, non-receptor type 6 antikoerper, protein tyrosine phosphatase, non-receptor type 6 L homeolog antikoerper, PTPN6 antikoerper, Ptpn6 antikoerper, ptpn6 antikoerper, ptpn6.L antikoerper
    Gen-ID
    5777
    Pathways
    JAK-STAT Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling
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