SQSTM1 Antikörper (AA 195-205) (PerCP)
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- Target Alle SQSTM1 Antikörper anzeigen
- SQSTM1 (Sequestosome 1 (SQSTM1))
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Bindungsspezifität
- AA 195-205
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SQSTM1 Antikörper ist konjugiert mit PerCP
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Ubiquitously expressed.,Detects ~60 kDa. Band at 40 kDa is isoform 2.
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Peptide Affinity Purified
- Immunogen
- Synthetic peptide from the N-terminal to mid of Human SQSTM1 (aa. 195-205)
- Isotyp
- IgG
- Top Product
- Discover our top product SQSTM1 Primärantikörper
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- Applikationshinweise
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Kommentare
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A 1:1000 dilution of ABIN5066098 was sufficient for detection of SQSTM1 in 15 μg of Human HeLa Cell Lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
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- Target
- SQSTM1 (Sequestosome 1 (SQSTM1))
- Andere Bezeichnung
- SQSTM1 (SQSTM1 Produkte)
- Synonyme
- SQSTM1 antikoerper, sqstm1 antikoerper, MGC79491 antikoerper, A170 antikoerper, OSIL antikoerper, PDB3 antikoerper, ZIP3 antikoerper, p60 antikoerper, p62 antikoerper, p62B antikoerper, OSF-6 antikoerper, Osi antikoerper, STAP antikoerper, ZIP antikoerper, sb:cb621 antikoerper, zgc:85784 antikoerper, sequestosome 1 antikoerper, sequestosome 1 L homeolog antikoerper, SQSTM1 antikoerper, sqstm1 antikoerper, Sqstm1 antikoerper, sqstm1.L antikoerper
- Hintergrund
- SQSTM1 or Sequestome 1 (p62) is a ubiquitin binding protein that interacts with ubiqutin, providing a scaffold for several signaling proteins and triggering degradation of proteins throught the proteasome or lysossome. This gene regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Mutations in this gene result in sporadic and familial Paget disease of bone. SQSTM1 also binds autophagosomal membrane protein LC3/ATG8.
- Gen-ID
- 8878
- NCBI Accession
- NP_001135770
- UniProt
- Q13501
- Pathways
- NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie
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