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SQSTM1 Antikörper (AA 232-356)

Name: SQSTM1 Antikörper (AA 232-356)
Brand: antibodies-online
SKU: ABIN1724836
Price: 520.24 EUR
Availability: InStock

SQSTM1 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Maus Monoclonal 5H7E2 unconjugated

Western blot analysis using SQSTM1 mouse mAb against Hela (1), Jurkat (2), THP-1 (3), HEK293 (4), A549 (5), MCF-7 (6), HepG2 (7), COS7 (8) and SK-BR-3 (9) cell lysate. (SQSTM1 Antikörper (AA 232-356))

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (SQSTM1 Antikörper (AA 232-356))

ELISA

Flow cytometric analysis of HEK293 cells using SQSTM1 mouse mAb (green) and negative control (red). (SQSTM1 Antikörper (AA 232-356))

FACS

Western blot analysis using SQSTM1 mAb against human SQSTM1 recombinant protein. (SQSTM1 Antikörper (AA 232-356))

Western blot analysis using SQSTM1 mAb against HEK293 (1) and SQSTM1 (AA: 232-356)-hIgGFc transfected HEK293 (2) cell lysate. (SQSTM1 Antikörper (AA 232-356))

Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using SQSTM1 mouse mAb with DAB staining. (SQSTM1 Antikörper (AA 232-356))

IHC

Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using SQSTM1 mouse mAb with DAB staining. (SQSTM1 Antikörper (AA 232-356))

IHC

7 Abbildungen

(1 reference)

Produktnummer ABIN1724836

Datenblatt (PDF)

Target Alle SQSTM1 Antikörper anzeigen

SQSTM1 (Sequestosome 1 (SQSTM1))
Bindungsspezifität
19

17

15

13

8

7

7

7

7

6

6

5

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 232-356
Reaktivität
154

64

61

18

4

4

4

4

3

2

2

2

1

1

1

1
Human
Wirt
129

23

1

1
Maus
Passende Sekundärantikörper
Klonalität
128

26
Monoklonal
Konjugat
75

11

10

7

7

6

5

5

5

5

5

5

1

1

1

1

1

1

1

1
Dieser SQSTM1 Antikörper ist unkonjugiert
Applikation
104

57

41

39

23

18

16

16

14

13

9

5

3

2

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Aufreinigung

Purified

Immunogen

Purified recombinant fragment of human SQSTM1 (AA: 232-356) expressed in E. Coli.

Klon

5H7E2

Isotyp

IgG1

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Applikationshinweise

Recommended Dilution:
ELISA: 1/10000
WB: 1/500 - 1/2000
IHC: 1/200 - 1/1000
FCM: 1/200 - 1/400

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

PBS with 0.05 % sodium azide and 0.5 % protein stabilizer

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store at 4 °C or at -20 °C for long term.
Inoue, Suzuki, Mitsuishi, Miki, Suzuki, Sugawara, Watanabe, Sakurada, Endo, Uruno, Sasano, Nakagawa, Satoh, Tanaka, Kubo, Motohashi, Yamamoto: "Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma." in: Cancer science, Vol. 103, Issue 4, pp. 760-6, (2012) (PubMed).
Target

SQSTM1 (Sequestosome 1 (SQSTM1))

Andere Bezeichnung

SQSTM1 (SQSTM1 Produkte)

Synonyme

SQSTM1 antikoerper, sqstm1 antikoerper, MGC79491 antikoerper, A170 antikoerper, OSIL antikoerper, PDB3 antikoerper, ZIP3 antikoerper, p60 antikoerper, p62 antikoerper, p62B antikoerper, OSF-6 antikoerper, Osi antikoerper, STAP antikoerper, ZIP antikoerper, sb:cb621 antikoerper, zgc:85784 antikoerper, sequestosome 1 antikoerper, sequestosome 1 L homeolog antikoerper, SQSTM1 antikoerper, sqstm1 antikoerper, Sqstm1 antikoerper, sqstm1.L antikoerper

Hintergrund

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Molekulargewicht

47.7 kDa

Gen-ID

8878

HGNC

8878

Pathways

NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie