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CD25 Antikörper

IL2RA Reaktivität: Human FACS Wirt: Maus Monoclonal 7G7B6 unconjugated
Produktnummer ABIN5027863
  • Target Alle CD25 (IL2RA) Antikörper anzeigen
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    Reaktivität
    • 182
    • 121
    • 38
    • 9
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 146
    • 92
    • 78
    • 2
    • 1
    Maus
    Klonalität
    • 239
    • 76
    • 2
    Monoklonal
    Konjugat
    • 110
    • 32
    • 28
    • 27
    • 21
    • 11
    • 8
    • 8
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD25 Antikörper ist unkonjugiert
    Applikation
    • 214
    • 91
    • 57
    • 50
    • 42
    • 36
    • 22
    • 16
    • 14
    • 14
    • 10
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Aufreinigung
    Protein G Chromatography
    Immunogen
    Recombinant human CD25 protein was used as an imunogen for this antidody.
    Klon
    7G7B6
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product IL2RA Primärantikörper
  • Applikationshinweise
    FACS: 0.5-1 μg/10^6 cells
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    PBS containing 0.05 % BSA, PH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • Target
    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
    Andere Bezeichnung
    hCD25 (IL2RA Produkte)
    Synonyme
    CD25 antikoerper, IDDM10 antikoerper, IL2R antikoerper, TCGFR antikoerper, IL2RAC antikoerper, IL-2RA antikoerper, Il2r antikoerper, Ly-43 antikoerper, interleukin 2 receptor subunit alpha antikoerper, interleukin-2 receptor subunit alpha-like antikoerper, interleukin 2 receptor, alpha chain antikoerper, IL2RA antikoerper, Il2ra antikoerper, LOC100222957 antikoerper
    Hintergrund
    CD25 is the alpha chain of the IL-2 receptor. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2. Though CD25 has been shown to influence effector function of lymphocytes, it is thought to play a greater role in immune tolerance in mice. Constitutive expression of CD25 on Treg cells is thought to be crucial to their survival and maintenance of immune homeostasis. Expression of CD25 and its role in immunology may be species dependent, since CD25 appears to play a larger role in T-cell effector responses in humans compared to mice, and may be somewhat dispensable for the maintenance of Treg cells as seen in patients treated with CD25-blocking antibodies.
    Gen-ID
    3559
    UniProt
    P01589
    Pathways
    JAK-STAT Signalweg, Growth Factor Binding, Activated T Cell Proliferation
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