GRP94 Antikörper (AA 420-700)

Produktnummer ABIN5027240

Produktdetails anti-GRP94 Antikörper

Target: GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))

Bindungsspezifität: AA 420-700

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRP94 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant GRP94 protein (amino acids 420-700) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu GRP94

Target: GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))

Andere Bezeichnung: GRP94 (HSP90B1 Produkte)

Synonyme: ecgp antikoerper, gp96 antikoerper, tra1 antikoerper, grp94 antikoerper, DDBDRAFT_0206450 antikoerper, DDBDRAFT_0215015 antikoerper, DDB_0206450 antikoerper, DDB_0215015 antikoerper, TRA1 antikoerper, HSP90B1 antikoerper, ERp99 antikoerper, GRP94 antikoerper, TA-3 antikoerper, Targ2 antikoerper, Tra-1 antikoerper, Tra1 antikoerper, endoplasmin antikoerper, GP96 antikoerper, fb61d09 antikoerper, tra-1 antikoerper, wu:fb61d09 antikoerper, wu:fq25g01 antikoerper, Grp94 antikoerper, ECGP antikoerper, Gp96 antikoerper, ppk98 antikoerper, hsp108 antikoerper, heat shock protein 90kDa beta (Grp94), member 1 antikoerper, heat shock protein Hsp90 family protein antikoerper, 94 kD glucose-regulated protein antikoerper, heat shock protein 90 beta family member 1 antikoerper, heat shock protein 90, beta (Grp94), member 1 antikoerper, heat shock protein 90, beta (grp94), member 1 antikoerper, heat shock protein 90kDa beta family member 1 L homeolog antikoerper, hsp90b1 antikoerper, grp94 antikoerper, HSP90B1 antikoerper, Hsp90b1 antikoerper, hsp90b1.L antikoerper

Hintergrund: GRP94 (94 kDa glucose-regulated protein) is a 92 kDa protein belonging to the heat shock protein 90 family of molecular chaperones. GRP94 is mainly involved in protein folding, stabilization and refolding of denatured proteins. GRP94 has also been reported to trigger CTL expansion and maturation of human monocytes-derived dendritic cells (MDDC). GRP94 is also involved in inducing tumor and is used as a potential marker in breast cancer. GRP94 is localized in endoplasmic reticulum lumen and melanosome. GRP94 is highly expressed in melanoma or liver metastases of colon carcinoma cells and human gastric carcinoma.

Molekulargewicht: 92 kDa

Gen-ID: 7184

UniProt: P14625

Pathways: Thyroid Hormone Synthesis, Activation of Innate immune Response, ER-Nucleus Signaling, Toll-Like Receptors Cascades