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GRP94 Antikörper

HSP90B1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Huhn, Hamster, Hund, Kaninchen, Schwein, Meerschweinchen, Affe, Schaf, Pferd, Xenopus laevis WB, IHC, IF, FACS, StM Wirt: Ratte Monoclonal 9G10-F8-2 unconjugated
Produktnummer ABIN6940802
  • Target Alle GRP94 (HSP90B1) Antikörper anzeigen
    GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))
    Reaktivität
    • 132
    • 85
    • 54
    • 39
    • 34
    • 30
    • 29
    • 29
    • 27
    • 27
    • 25
    • 25
    • 24
    • 16
    • 10
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Huhn, Hamster, Hund, Kaninchen, Schwein, Meerschweinchen, Affe, Schaf, Pferd, Xenopus laevis
    Wirt
    • 93
    • 39
    • 24
    • 2
    • 1
    Ratte
    Klonalität
    • 94
    • 65
    Monoklonal
    Konjugat
    • 69
    • 12
    • 11
    • 11
    • 10
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GRP94 Antikörper ist unkonjugiert
    Applikation
    • 151
    • 82
    • 68
    • 62
    • 49
    • 46
    • 39
    • 21
    • 13
    • 13
    • 12
    • 11
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)
    Spezifität
    Recognizes a protein of 94 kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp's are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Purified glucose regulated protein 94 (grp94) from chicken oviducts
    Klon
    9G10-F8-2
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product HSP90B1 Primärantikörper
  • Applikationshinweise

    Positive Control: HepG2, U20S cells. About 50 % of breast tumors express grp94 protein.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1.0 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))
    Andere Bezeichnung
    HSP90B1 (HSP90B1 Produkte)
    Synonyme
    ecgp antikoerper, gp96 antikoerper, tra1 antikoerper, grp94 antikoerper, DDBDRAFT_0206450 antikoerper, DDBDRAFT_0215015 antikoerper, DDB_0206450 antikoerper, DDB_0215015 antikoerper, TRA1 antikoerper, HSP90B1 antikoerper, ERp99 antikoerper, GRP94 antikoerper, TA-3 antikoerper, Targ2 antikoerper, Tra-1 antikoerper, Tra1 antikoerper, endoplasmin antikoerper, GP96 antikoerper, fb61d09 antikoerper, tra-1 antikoerper, wu:fb61d09 antikoerper, wu:fq25g01 antikoerper, Grp94 antikoerper, ECGP antikoerper, Gp96 antikoerper, ppk98 antikoerper, hsp108 antikoerper, heat shock protein 90kDa beta (Grp94), member 1 antikoerper, heat shock protein Hsp90 family protein antikoerper, 94 kD glucose-regulated protein antikoerper, heat shock protein 90 beta family member 1 antikoerper, heat shock protein 90, beta (Grp94), member 1 antikoerper, heat shock protein 90, beta (grp94), member 1 antikoerper, heat shock protein 90kDa beta family member 1 L homeolog antikoerper, hsp90b1 antikoerper, grp94 antikoerper, HSP90B1 antikoerper, Hsp90b1 antikoerper, hsp90b1.L antikoerper
    Molekulargewicht
    94kDa
    Gen-ID
    7184
    UniProt
    P14625
    Pathways
    Thyroid Hormone Synthesis, Activation of Innate immune Response, ER-Nucleus Signaling, Toll-Like Receptors Cascades
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