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Cyclin D1 Antikörper (AA 108-322)

Name: Cyclin D1 Antikörper (AA 108-322)
SKU: ABIN5027125
Availability: OutOfStock

CCND1 Reaktivität: Human IHC Wirt: Maus Monoclonal ABM47F5 unconjugated

Image no. 1 for anti-Cyclin D1 (CCND1) (AA 108-322) antibody (ABIN5027125) (Cyclin D1 Antikörper (AA 108-322))

1 image

Produktnummer ABIN5027125

Datenblatt (PDF)

Target Alle Cyclin D1 (CCND1) Antikörper anzeigen

Cyclin D1 (CCND1)
Bindungsspezifität
22

21

16

16

13

10

9

7

7

7

7

7

6

6

5

5

3

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 108-322
Reaktivität
233

129

123

38

19

18

17

10

9

7

4

3

3

3

3

2

1

1

1

1

1
Human
Wirt
201

56

1
Maus
Passende Sekundärantikörper
Klonalität
192

64
Monoklonal
Konjugat
115

28

20

9

7

5

5

5

5

5

5

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1
Dieser Cyclin D1 Antikörper ist unkonjugiert
Applikation
196

88

67

65

41

32

27

27

22

20

20

13

6

5

3

2

2

2

1

1

1
Immunohistochemistry (IHC)

Aufreinigung

Protein G Chromatography

Immunogen

A partial length recombinant Cyclin D1 protein (amino acids 108-322) was used as the immunogen for this antibody.

Klon

ABM47F5

Isotyp

IgG2a kappa

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Applikationshinweise

IHC: 5-10 μg/mL

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

0.5 mg/mL

Buffer

PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Target

Cyclin D1 (CCND1)

Andere Bezeichnung

Cyclin D1 (CCND1 Produkte)

Synonyme

BCL1 antikoerper, D11S287E antikoerper, PRAD1 antikoerper, U21B31 antikoerper, AI327039 antikoerper, CycD1 antikoerper, Cyl-1 antikoerper, bcl-1 antikoerper, cD1 antikoerper, cb161 antikoerper, cycd1 antikoerper, etID37810.7 antikoerper, fb52e01 antikoerper, fc45c08 antikoerper, fc83a12 antikoerper, id:ibd1198 antikoerper, wu:fb52e01 antikoerper, wu:fc45c08 antikoerper, wu:fc83a12 antikoerper, ccnd1b antikoerper, prad1 antikoerper, ccnd1 antikoerper, ccnd1a antikoerper, bcl1 antikoerper, d11s287e antikoerper, u21b31 antikoerper, CCND1 antikoerper, cyclin D1 antikoerper, cyclin D1 S homeolog antikoerper, cyclin D1 L homeolog antikoerper, CCND1 antikoerper, Ccnd1 antikoerper, ccnd1 antikoerper, ccnd1.S antikoerper, ccnd1.L antikoerper

Hintergrund

Cyclin D1 (CCND1) is an important positive regulator of the G1/S phase of the cell cycle. It regulate cell cycle transition from G1 phase to S phase It is a well-established human oncogene which is frequently amplified or overexpressed in cancers (25409185). Cyclin D1b is one of two proteins translated from Cyclin D1 transcripts (isoforms a and b) that are generated due to gene polymorphism. Low Cyclin D1b expression in cervical cancer tissue, with an expression level in moderately or poorly differentiated tissues was significantly lower than that in well-differentiated tissues (25120779). Diseases associated with CCND1 include multiple myeloma and mantle cell lymphoma.

Gen-ID

23582

UniProt

O95273

Pathways

PI3K-Akt Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, ER-Nucleus Signaling