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Caspase 12 Antikörper (AA 100-321)

CASP12 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5027075
  • Target Alle Caspase 12 (CASP12) Antikörper anzeigen
    Caspase 12 (CASP12) (Caspase 12 (Gene/pseudogene) (CASP12))
    Bindungsspezifität
    • 16
    • 15
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-321
    Reaktivität
    • 62
    • 53
    • 33
    Human
    Wirt
    • 88
    • 3
    • 1
    Kaninchen
    Klonalität
    • 89
    • 3
    Polyklonal
    Konjugat
    • 39
    • 8
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Caspase 12 Antikörper ist unkonjugiert
    Applikation
    • 78
    • 40
    • 29
    • 28
    • 26
    • 26
    • 21
    • 19
    • 10
    • 6
    • 5
    • 5
    • 1
    Western Blotting (WB)
    Aufreinigung
    Protein A Chromatography
    Immunogen
    A partial length recombinant Caspase-12 protein (amino acids 100-321) was used as the immunogen for this antibody.
    Isotyp
    IgG
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  • Applikationshinweise
    WB: 4-6 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    PBS containing 0.05 % BSA, PH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • Target
    Caspase 12 (CASP12) (Caspase 12 (Gene/pseudogene) (CASP12))
    Andere Bezeichnung
    Caspase-12 (CASP12 Produkte)
    Synonyme
    Caspase-12 antikoerper, CASP-12 antikoerper, CASP12P1 antikoerper, caspase 12 antikoerper, caspase 12 (gene/pseudogene) antikoerper, Casp12 antikoerper, CASP12 antikoerper
    Hintergrund
    Caspase 12 belongs to a family of enzymes called caspases that is highly related to members of the ICE subfamily. Other caspases cleave their substrates at C-terminal aspartic acid residue but caspase 12 does not have protease properties rather it processes inflammatory cytokines. It is involved in the activation cascade of caspases responsible for apoptosis execution. Diseases associated with CASP12 include sepsis and prion disease. Caspase 12 is mainly expressed in skeletal muscle and lung.
    Molekulargewicht
    27 kDa
    Gen-ID
    101000000
    UniProt
    Q6UXS9
    Pathways
    Apoptose, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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