GTF2H1 Antikörper

Produktnummer ABIN498311

Produktdetails anti-GTF2H1 Antikörper

Target: GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTF2H1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of TFIIH p62 protein. (region surrounding Ala32)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: Affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % (by SDS-PAGE)

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu GTF2H1

Target: GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))

Andere Bezeichnung: GTF2H1 / BTF2 (GTF2H1 Produkte)

Synonyme: 62kDa antikoerper, AW743425 antikoerper, AW822074 antikoerper, BTF2 p62 antikoerper, C77871 antikoerper, p62 antikoerper, GTF2H1 antikoerper, BTF2 antikoerper, P62 antikoerper, TFB1 antikoerper, TFIIH antikoerper, gtf2h1 antikoerper, MGC53309 antikoerper, btf2 antikoerper, tfiih antikoerper, CG8151 antikoerper, Dmel\\CG8151 antikoerper, Dmp62 antikoerper, TfBl antikoerper, l(2)06949 antikoerper, l(2)06950 antikoerper, zgc:92126 antikoerper, general transcription factor IIH subunit 1 antikoerper, general transcription factor II H, polypeptide 1 antikoerper, general transcription factor IIH subunit 1 L homeolog antikoerper, Transcription factor B1 antikoerper, general transcription factor IIH, polypeptide 1 antikoerper, GTF2H1 antikoerper, Gtf2h1 antikoerper, gtf2h1.L antikoerper, gtf2h1 antikoerper, Tfb1 antikoerper

Hintergrund: Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription actors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFII. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.Synonyms: BTF2-p62, Basic transcription factor 2 62 kDa subunit, General transcription factor IIH polypeptide 1, General transcription factor IIH subunit 1, TFIIH, TFIIH basal transcription factor complex p62 subunit

Molekulargewicht: approx. 57 kDa

Gen-ID: 2965

NCBI Accession: NP_001135779

UniProt: P32780

Pathways: DNA Reparatur