GTF2H1 Antikörper (N-Term)

Produktnummer ABIN6256996

Produktdetails anti-GTF2H1 Antikörper

Target: GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTF2H1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: TF2H1 Antibody detects endogenous levels of total TF2H1.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TF2H1, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu GTF2H1

Target: GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))

Andere Bezeichnung: GTF2H1 (GTF2H1 Produkte)

Synonyme: 62kDa antikoerper, AW743425 antikoerper, AW822074 antikoerper, BTF2 p62 antikoerper, C77871 antikoerper, p62 antikoerper, GTF2H1 antikoerper, BTF2 antikoerper, P62 antikoerper, TFB1 antikoerper, TFIIH antikoerper, gtf2h1 antikoerper, MGC53309 antikoerper, btf2 antikoerper, tfiih antikoerper, CG8151 antikoerper, Dmel\\CG8151 antikoerper, Dmp62 antikoerper, TfBl antikoerper, l(2)06949 antikoerper, l(2)06950 antikoerper, zgc:92126 antikoerper, general transcription factor IIH subunit 1 antikoerper, general transcription factor II H, polypeptide 1 antikoerper, general transcription factor IIH subunit 1 L homeolog antikoerper, Transcription factor B1 antikoerper, general transcription factor IIH, polypeptide 1 antikoerper, GTF2H1 antikoerper, Gtf2h1 antikoerper, gtf2h1.L antikoerper, gtf2h1 antikoerper, Tfb1 antikoerper

Hintergrund:

Description: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.

Gene: GTF2H1

Molekulargewicht: 57 kDa

Gen-ID: 2965

UniProt: P32780

Pathways: DNA Reparatur