GTF2H1 Antikörper (AA 1-425)

Produktnummer ABIN6141498

Produktdetails anti-GTF2H1 Antikörper

Target: GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))

Bindungsspezifität: AA 1-425

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTF2H1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: MATSSEEVLL IVKKVRQKKQ DGALYLMAER IAWAPEGKDR FTISHMYADI KCQKISPEGK AKIQLQLVLH AGDTTNFHFS NESTAVKERD AVKDLLQQLL PKFKRKANKE LEEKNRMLQE DPVLFQLYKD LVVSQVISAE EFWANRLNVN ATDSSSTSNH KQDVGISAAF LADVRPQTDG CNGLRYNLTS DIIESIFRTY PAVKMKYAEN VPHNMTEKEF WTRFFQSHYF HRDRLNTGSK DLFAECAKID EKGLKTMVSL GVKNPLLDLT ALEDKPLDEG YGISSVPSAS NSKSIKENSN AAIIKRFNHH SAMVLAAGLR KQEAQNEQTS EPSNMDGNSG DADCFQPAVK RAKLQESIEY EDLGKNNSVK TIALNLKKSD RYYHGPTPIQ SLQYATSQDI INSFQSIRQE MEAYTPKLTQ VLSSS

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-425 of human GTF2H1 (NP_001135779.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:1000,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GTF2H1

Target: GTF2H1 (General Transcription Factor IIH, Polypeptide 1, 62kDa (GTF2H1))

Andere Bezeichnung: GTF2H1 (GTF2H1 Produkte)

Synonyme: 62kDa antikoerper, AW743425 antikoerper, AW822074 antikoerper, BTF2 p62 antikoerper, C77871 antikoerper, p62 antikoerper, GTF2H1 antikoerper, BTF2 antikoerper, P62 antikoerper, TFB1 antikoerper, TFIIH antikoerper, gtf2h1 antikoerper, MGC53309 antikoerper, btf2 antikoerper, tfiih antikoerper, CG8151 antikoerper, Dmel\\CG8151 antikoerper, Dmp62 antikoerper, TfBl antikoerper, l(2)06949 antikoerper, l(2)06950 antikoerper, zgc:92126 antikoerper, general transcription factor IIH subunit 1 antikoerper, general transcription factor II H, polypeptide 1 antikoerper, general transcription factor IIH subunit 1 L homeolog antikoerper, Transcription factor B1 antikoerper, general transcription factor IIH, polypeptide 1 antikoerper, GTF2H1 antikoerper, Gtf2h1 antikoerper, gtf2h1.L antikoerper, gtf2h1 antikoerper, Tfb1 antikoerper

Hintergrund: Component of the general transcription and DNA repair factor IIH (TFIIH core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.,GTF2H1,BTF2,P62,TFB1,TFIIH,Epigenetics & Nuclear Signaling,GTF2H1

Molekulargewicht: 48 kDa/62 kDa

Gen-ID: 2965

UniProt: P32780

Pathways: DNA Reparatur