TIGIT Antikörper (AA 12-142)

Produktnummer ABIN4955607

Produktdetails anti-TIGIT Antikörper

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Bindungsspezifität: AA 12-142

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIGIT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity

Immunogen: A portion of amino acids 12-142 from the human protein was used as the immunogen for this TIGIT antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the TIGIT antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the TIGIT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu TIGIT

Target: TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))

Andere Bezeichnung: TIGIT (TIGIT Produkte)

Synonyme: VSIG9 antikoerper, VSTM3 antikoerper, WUCAM antikoerper, ENSMUSG00000071552 antikoerper, Vstm3 antikoerper, RGD1563191 antikoerper, T-cell immunoreceptor with Ig and ITIM domains antikoerper, T cell immunoreceptor with Ig and ITIM domains antikoerper, TIGIT antikoerper, Tigit antikoerper

Hintergrund: TIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

UniProt: Q495A1

Pathways: Cancer Immune Checkpoints