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TIGIT Produkte

(T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))
This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity\; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009].

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Ausgewählte TIGIT Kategorien

TIGIT Antikörper

High quality antibodies with extensive validation data.

TIGIT ELISA Kits

Reliable ELISA kits for a wide range of species.

TIGIT Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TIGIT Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, ICC, IP
Validierungen
  • (5)
Kat. Nr. ABIN7439486
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, ICC, FACS, Neut
Validierungen
  • (4)
Kat. Nr. ABIN7193227
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC, FACS, Coat, StM
Validierungen
  • (4)
Kat. Nr. ABIN6939305
Menge 100 μg
Datenblatt Datenblatt

Empfohlene TIGIT ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959836
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6730832
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN4884793
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TIGIT Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (6)
Kat. Nr. ABIN7275729
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (6)
Kat. Nr. ABIN7275728
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7275730
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TIGIT Produkten

Bai, Gao, Hu, Liu, Li, Dong, Huang, Zhu, Zhou, Li, Shao: "Self-Assembled Multivalent Aptamer Nanoparticles with Potential CAR-like Characteristics Could Activate T Cells and Inhibit Melanoma Growth." in: Molecular therapy oncolytics, Vol. 17, pp. 9-20, (2020) (PubMed).

Brockmann, Soukou, Steglich, Czarnewski, Zhao, Wende, Bedke, Ergen, Manthey, Agalioti, Geffken, Seiz, Parigi, Sorini, Geginat, Fujio, Jacobs, Roesch, Izbicki, Lohse, Flavell, Krebs, Gustafsson et al.: "Molecular and functional heterogeneity of IL-10-producing CD4+ T cells. ..." in: Nature communications, Vol. 9, Issue 1, pp. 5457, (2019) (PubMed).

Nuñez, Ziblat, Secchiari, Torres, Sierra, Raffo Iraolagoitia, Araya, Domaica, Fuertes, Zwirner: "Human M2 Macrophages Limit NK Cell Effector Functions through Secretion of TGF-β and Engagement of CD85j." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 3, pp. 1008-1015, (2018) (PubMed).

Downs-Canner, Berkey, Delgoffe, Edwards, Curiel, Odunsi, Bartlett, Obermajer: "Suppressive IL-17A+Foxp3+and ex-Th17 IL-17AnegFoxp3+Tregcells are a source of tumour-associated Tregcells." in: Nature communications, Vol. 8, pp. 14649, (2017) (PubMed).

Yasuma, Yasunaga, Takemoto, Sugata, Mitobe, Takenouchi, Nakagawa, Suzuki, Matsuoka: "HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT)." in: PLoS pathogens, Vol. 12, Issue 1, pp. e1005372, (2016) (PubMed).

Gur, Ibrahim, Isaacson, Yamin, Abed, Gamliel, Enk, Bar-On, Stanietsky-Kaynan, Coppenhagen-Glazer, Shussman, Almogy, Cuapio, Hofer, Mevorach, Tabib, Ortenberg, Markel, Miklić, Jonjic, Brennan, Garrett et al.: "Binding of the Fap2 protein of Fusobacterium nucleatum to human inhibitory receptor TIGIT protects tumors from immune cell attack. ..." in: Immunity, Vol. 42, Issue 2, pp. 344-55, (2015) (PubMed).

Zhang, Wang, Zhou, Liang, Bai, Yang, Gu, Gao, Dong, Zhu, Chen: "Increased expression of TIGIT on CD4+ T cells ameliorates immune-mediated bone marrow failure of aplastic anemia." in: Journal of cellular biochemistry, Vol. 115, Issue 11, pp. 1918-27, (2014) (PubMed).

Stanietsky, Rovis, Glasner, Seidel, Tsukerman, Yamin, Enk, Jonjic, Mandelboim: "Mouse TIGIT inhibits NK-cell cytotoxicity upon interaction with PVR." in: European journal of immunology, Vol. 43, Issue 8, pp. 2138-50, (2013) (PubMed).

Synonyme und alternative Namen zu TIGIT

T-cell immunoreceptor with Ig and ITIM domains (TIGIT), T cell immunoreceptor with Ig and ITIM domains (Tigit), ENSMUSG00000071552, RGD1563191, VSIG9, VSTM3, Vstm3, WUCAM

Bezeichner auf Proteinebene für TIGIT

  • T-cell immunoreceptor with Ig and ITIM domains
  • V-set and immunoglobulin domain containing 9
  • V-set and immunoglobulin domain-containing protein 9
  • V-set and transmembrane domain containing 3
  • V-set and transmembrane domain-containing protein 3
  • Washington University cell adhesion molecule
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