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TIM3 Produkte

(Hepatitis A Virus Cellular Receptor 2 (TIM 3))
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011].

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Ausgewählte TIM3 Kategorien

TIM3 Antikörper

High quality antibodies with extensive validation data.

TIM3 ELISA Kits

Reliable ELISA kits for a wide range of species.

TIM3 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TIM3 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, FACS, ELISA, IF
Validierungen
  • (8)
Kat. Nr. ABIN185571
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC, Coat, StM
Validierungen
  • (5)
Kat. Nr. ABIN6940963
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (5)
  • (3)
Kat. Nr. ABIN1881402
Menge 400 μL
Datenblatt Datenblatt

Empfohlene TIM3 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956490
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6956491
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN5692220
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TIM3 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7275736
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7275739
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7275740
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TIM3 Produkten

Wu, Li, Xia, Tian, Kong, Wang, Gu, Zhang, Tu, Xie, Yang, Lu, Jiang, Ying: "Identification of Human Single-Domain Antibodies against SARS-CoV-2." in: Cell host & microbe, (2020) (PubMed).

Yang, Ying, Wu, Chen: "sTim-3 alleviates liver injury via regulation of the immunity microenvironment and autophagy." in: Cell death discovery, Vol. 6, pp. 62, (2020) (PubMed).

Bai, Gao, Hu, Liu, Li, Dong, Huang, Zhu, Zhou, Li, Shao: "Self-Assembled Multivalent Aptamer Nanoparticles with Potential CAR-like Characteristics Could Activate T Cells and Inhibit Melanoma Growth." in: Molecular therapy oncolytics, Vol. 17, pp. 9-20, (2020) (PubMed).

Das, Choudhury, Jagadeeshaprasad, Kulkarni, Mondal, Bandyopadhyay: "Proteomic analysis detects deregulated reverse cholesterol transport in human subjects with ST-segment elevation myocardial infarction." in: Journal of proteomics, Vol. 222, pp. 103796, (2020) (PubMed).

Franchini, Lanvin, Tosolini, Patras de Campaigno, Cammas, Péricart, Scarlata, Lebras, Rossi, Ligat, Pont, Arimondo, Laurent, Ayyoub, Despas, Lapeyre-Mestre, Millevoi, Fournié: "Microtubule-Driven Stress Granule Dynamics Regulate Inhibitory Immune Checkpoint Expression in T Cells." in: Cell reports, Vol. 26, Issue 1, pp. 94-107.e7, (2019) (PubMed).

Wingrove, Liu, Patel, Arnal-Estapé, Cai, Melnick, Politi, Monteiro, Zhu, Valiente, Kluger, Chiang, Nguyen: "Transcriptomic Hallmarks of Tumor Plasticity and Stromal Interactions in Brain Metastasis." in: Cell reports, Vol. 27, Issue 4, pp. 1277-1292.e7, (2019) (PubMed).

Klebanoff, Crompton, Leonardi, Yamamoto, Chandran, Eil, Sukumar, Vodnala, Hu, Ji, Clever, Black, Gurusamy, Kruhlak, Jin, Stroncek, Gattinoni, Feldman, Restifo: "Inhibition of AKT signaling uncouples T cell differentiation from expansion for receptor-engineered adoptive immunotherapy." in: JCI insight, Vol. 2, Issue 23, (2018) (PubMed).

Wang, Edilova, Wagar, Mujib, Singer, Bernard, Croughs, Lederman, Sereti, Fischl, Kremmer, Ostrowski, Routy, Watts: "Effect of IL-7 Therapy on Phospho-Ribosomal Protein S6 and TRAF1 Expression in HIV-Specific CD8 T Cells in Patients Receiving Antiretroviral Therapy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 2, pp. 558-564, (2018) (PubMed).

Roboz, Ritchie, Dault, Lam, Marshall, Cruz, Hsu, Hassane, Christos, Ippoliti, Scandura, Guzman: "Phase I trial of plerixafor combined with decitabine in newly diagnosed older patients with acute myeloid leukemia." in: Haematologica, Vol. 103, Issue 8, pp. 1308-1316, (2018) (PubMed).

DAngelo, Melchiori, Merchant, Bernstein, Glod, Kaplan, Grupp, Tap, Chagin, Binder, Basu, Lowther, Wang, Bath, Tipping, Betts, Ramachandran, Navenot, Zhang, Wells, Van Winkle, Kari, Trivedi, Holdich et al.: "Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 c259T Cells in Synovial Sarcoma. ..." in: Cancer discovery, Vol. 8, Issue 8, pp. 944-957, (2018) (PubMed).

Synonyme und alternative Namen zu TIM3

hepatitis A virus cellular receptor 2 (HAVCR2), hepatitis A virus cellular receptor 2 (Havcr2), HAVcr-2, HAVCR2, KIM-3, MGC140131, Tim-3, TIM-3, TIM3, Tim3, tim3, TIMD-3, TIMD3, Timd3

Bezeichner auf Proteinebene für TIM3

  • hepatitis A virus cellular receptor 2
  • T cell immunoglobulin mucin 3
  • T cell immunoglobulin mucin-3
  • T-cell immunoglobulin and mucin domain-containing protein 3
  • T-cell membrane protein 3
  • kidney injury molecule-3
  • HAVcr-2
  • T-cell immunoglobulin and mucin domain containing 3
  • TIMD-3
  • hepatitis A virus cellular receptor 2 homolog
  • TIM-3
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