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TIE1 Produkte

(tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].

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Ausgewählte TIE1 Kategorien

TIE1 Antikörper

High quality antibodies with extensive validation data.

TIE1 ELISA Kits

Reliable ELISA kits for a wide range of species.

TIE1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TIE1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (6)
Kat. Nr. ABIN2683015
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p), ICC, IHC (fro)
Validierungen
  • (4)
Kat. Nr. ABIN7442504
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p), ICC, IHC (fro)
Validierungen
  • (3)
Kat. Nr. ABIN7431122
Menge 100 μL
Datenblatt Datenblatt

Empfohlene TIE1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (6)
Kat. Nr. ABIN6730883
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6960330
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Zebrafish (Danio rerio)
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN1572722
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TIE1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3074168
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3121475
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3074167
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TIE1 Produkten

Leppänen, Saharinen, Alitalo: "Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 17, pp. 4376-4381, (2017) (PubMed).

Morooka, Futaki, Sato-Nishiuchi, Nishino, Totani, Shimono, Nakano, Nakajima, Mochizuki, Sekiguchi: "Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling." in: Circulation research, Vol. 120, Issue 8, pp. 1276-1288, (2017) (PubMed).

Hakanpaa, Sipila, Leppanen, Gautam, Nurmi, Jacquemet, Eklund, Ivaska, Alitalo, Saharinen: "Endothelial destabilization by angiopoietin-2 via integrin β1 activation." in: Nature communications, Vol. 6, pp. 5962, (2015) (PubMed).

Saulle, Guerriero, Petronelli, Coppotelli, Gabbianelli, Morsilli, Spinello, Pelosi, Castelli, Testa, Coppola: "Autocrine role of angiopoietins during megakaryocytic differentiation." in: PLoS ONE, Vol. 7, Issue 7, pp. e39796, (2012) (PubMed).

Marron, Singh, Tahir, Kavumkal, Kim, Koh, Brindle: "Regulated proteolytic processing of Tie1 modulates ligand responsiveness of the receptor-tyrosine kinase Tie2." in: The Journal of biological chemistry, Vol. 282, Issue 42, pp. 30509-17, (2007) (PubMed).

Kim, Shin, Kim, Choi, Byun, Jeon, Suh, Kim: "Interaction between Tie receptors modulates angiogenic activity of angiopoietin2 in endothelial progenitor cells." in: Cardiovascular research, Vol. 72, Issue 3, pp. 394-402, (2006) (PubMed).

Lin, Lee, Sun: "Functions of the activation loop in Csk protein-tyrosine kinase." in: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 24072-7, (2003) (PubMed).

Huang, Chen, Inoue, Chen: "Tyrosine phosphorylation of I-kappa B kinase alpha/beta by protein kinase C-dependent c-Src activation is involved in TNF-alpha-induced cyclooxygenase-2 expression." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 9, pp. 4767-75, (2003) (PubMed).

Natarajan, Rajala, Chodosh: "Corneal IL-8 expression following adenovirus infection is mediated by c-Src activation in human corneal fibroblasts." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 12, pp. 6234-43, (2003) (PubMed).

Danet, Pan, Luongo, Bonnet, Simon: "Expansion of human SCID-repopulating cells under hypoxic conditions." in: The Journal of clinical investigation, Vol. 112, Issue 1, pp. 126-35, (2003) (PubMed).

Synonyme und alternative Namen zu TIE1

tyrosine kinase with immunoglobulin like and EGF like domains 1 (TIE1), tyrosine kinase with immunoglobulin-like and EGF-like domains 1 (Tie1), tyrosine-protein kinase receptor Tie-1 (CpipJ_CPIJ018933), endothelium-specific receptor tyrosine kinase 1 (tie1), D430008P04Rik, JTK14, TIE, tie-1

Bezeichner auf Proteinebene für TIE1

  • tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1
  • tyrosine-protein kinase receptor Tie-1
  • tyrosine kinase receptor 1
  • tyrosine kinase with immunoglobulin and epidermal growth factor homology domains
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