IDH2 Antikörper

Produktnummer ABIN4951404

Produktdetails anti-IDH2 Antikörper

Target: IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IDH2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Aufreinigung: Antigen affinity

Immunogen: Amino acids KDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDR of human IDH2 were used as the immunogen for the IDH2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the IDH2 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the IDH2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu IDH2

Target: IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

Andere Bezeichnung: IDH2 (IDH2 Produkte)

Synonyme: F6P23.14 antikoerper, F6P23_14 antikoerper, IDH-II antikoerper, NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 2 antikoerper, isocitrate dehydrogenase II antikoerper, isocitrate dehydrogenase subunit 2 antikoerper, D2HGA2 antikoerper, ICD-M antikoerper, IDH antikoerper, IDHM antikoerper, IDP antikoerper, IDPM antikoerper, mNADP-IDH antikoerper, E430004F23 antikoerper, IDPm antikoerper, Idh-2 antikoerper, wu:fb33c06 antikoerper, wu:fk31e05 antikoerper, wu:fq43b01 antikoerper, zgc:55485 antikoerper, idh2 antikoerper, IDH2 antikoerper, isocitrate dehydrogenase subunit 2 antikoerper, isocitrate dehydrogenase (NADP(+)) 2, mitochondrial antikoerper, isocitrate dehydrogenase 2 (NADP+), mitochondrial antikoerper, isocitrate dehydrogenase 2 (NADP+), mitochondrial S homeolog antikoerper, isocitrate dehydrogenase [NADP], mitochondrial antikoerper, IDH2 antikoerper, Idh2 antikoerper, idh2.S antikoerper, idh2 antikoerper, LOC100441867 antikoerper

Hintergrund: Isocitrate dehydrogenase [NADP], mitochondrial is an enzyme that in humans is encoded by the IDH2 gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.

UniProt: P48735

Pathways: Warburg Effekt