ACVR2B Antikörper (C-Term)
-
- Target Alle ACVR2B Antikörper anzeigen
- ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
-
Bindungsspezifität
- AA 431-466, C-Term
-
Reaktivität
- Human, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser ACVR2B Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Activin receptor type-2B(ACVR2B) detection. Tested with WB in Human,Rat.
- Sequenz
- VVHKKMRPTI KDHWLKHPGL AQLCVTIEEC WDHDAE
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
-
Rabbit IgG polyclonal antibody for Activin receptor type-2B(ACVR2B) detection. Tested with WB in Human,Rat.
Gene Name: activin A receptor type 2B
Protein Name: Activin receptor type-2B - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human ACVR2B (431-466aa VVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAE), identical to the related mouse and rat sequences.
- Isotyp
- IgG
- Top Product
- Discover our top product ACVR2B Primärantikörper
-
-
- Applikationshinweise
-
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
-
- Target
- ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
- Andere Bezeichnung
- ACVR2B (ACVR2B Produkte)
- Synonyme
- ACVR2B antikoerper, XAR1 antikoerper, actr-iib antikoerper, actriib antikoerper, ACTRIIB antikoerper, ActR-IIB antikoerper, HTX4 antikoerper, ActRIIB antikoerper, actr2b antikoerper, actrIIb antikoerper, wu:fj97d11 antikoerper, activin A receptor type 2B antikoerper, activin A receptor type 2B L homeolog antikoerper, activin A receptor type 2Ba antikoerper, activin receptor IIB antikoerper, ACVR2B antikoerper, acvr2b antikoerper, acvr2b.L antikoerper, Acvr2b antikoerper, acvr2ba antikoerper
- Hintergrund
-
Activin receptor type-2B is a protein that in humans is encoded by the ACVR2B gene. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This ACVR2B gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.
Synonyms: ActRIIB | ActR-IIB | ActR IIB | ACVR2B | ACVR-2B | ACVR 2B | HTX4 | MGC116908 | Q13705 - Gen-ID
- 93
- UniProt
- Q13705
- Pathways
- Hormone Transport, Cancer Immune Checkpoints
-