ACVR2B Antikörper (Extracellular Domain)

Produktnummer ABIN2745505

Produktdetails anti-ACVR2B Antikörper

Target: ACVR2B (Activin A Receptor, Type IIB (ACVR2B))

Bindungsspezifität: Extracellular Domain

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACVR2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Recognizes the extracellular domain of human and mouse ACTR-IIB.

Kreuzreaktivität: Human, Maus

Kreuzreaktivität (Details): Does not cross-react with related human proteins ActR-IIecd, BMPR-IIecd, BMPR-IAecd, BMPR-IBecd or ActR-Iecd.

Aufreinigung: Antigen affinity purified.

Immunogen: Recombinant extracellular domain (ecd) of mouse activin receptor IIB.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: In PBS with 1 mg/mL BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Details zu ACVR2B

Target: ACVR2B (Activin A Receptor, Type IIB (ACVR2B))

Andere Bezeichnung: Activin Receptor IIB (ACVR2B Produkte)

Synonyme: ACVR2B antikoerper, XAR1 antikoerper, actr-iib antikoerper, actriib antikoerper, ACTRIIB antikoerper, ActR-IIB antikoerper, HTX4 antikoerper, ActRIIB antikoerper, actr2b antikoerper, actrIIb antikoerper, wu:fj97d11 antikoerper, activin A receptor type 2B antikoerper, activin A receptor type 2B L homeolog antikoerper, activin A receptor type 2Ba antikoerper, activin receptor IIB antikoerper, ACVR2B antikoerper, acvr2b antikoerper, acvr2b.L antikoerper, Acvr2b antikoerper, acvr2ba antikoerper

Hintergrund: Activin Receptor IIB (ACTR-IIB) is a transmembrane receptor that forms an activin receptor complex with activin type-1 receptors (ACVR1, ACVR1B or ACVR1c). ACTR-IIB transduces the activin signal from the cell surface to the cytoplasm and regulates therefore many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary.

UniProt: P27040

Pathways: Hormone Transport, Cancer Immune Checkpoints