ACVR2B Produkte
(Activin A Receptor, Type IIB (ACVR2B))
Kategorien
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq, Jul 2008].
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Ausgewählte ACVR2B Kategorien
ACVR2B Antikörper
High quality antibodies with extensive validation data.
ACVR2B ELISA Kits
Reliable ELISA kits for a wide range of species.
ACVR2B Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ACVR2B Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat, Sheep, Zebrafish (Danio rerio)
Applikation
WB
Validierungen
- (5)
Kat. Nr.
ABIN2782110
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Rat
Applikation
WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validierungen
- (3)
Kat. Nr.
ABIN1714650
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN391162
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene ACVR2B ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6953430
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4881730
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6385086
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ACVR2B Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf21)
Validierungen
- (2)
Kat. Nr.
ABIN5569458
Menge
5 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1305815
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1305817
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ACVR2B Produkten
: "Modulation of noncanonical TGF-? signaling prevents cleft palate in Tgfbr2 mutant mice." in: The Journal of clinical investigation, Vol. 122, Issue 3, pp. 873-85, (2012) (PubMed).: "Myostatin is associated with age-related human muscle stem cell dysfunction." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 26, Issue 6, pp. 2509-21, (2012) (PubMed).
: "Expression of activin subunits and receptors in the developing human ovary: activin A promotes germ cell survival and proliferation before primordial follicle formation." in: Developmental biology, Vol. 266, Issue 2, pp. 334-45, (2004) (PubMed).
: "An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28036-44, (2004) (PubMed).
: "Inhibin, activin, follistatin, activin receptors and beta-glycan gene expression in the placental tissue of patients with pre-eclampsia." in: Molecular human reproduction, Vol. 9, Issue 4, pp. 199-203, (2003) (PubMed).
Synonyme und alternative Namen zu ACVR2B
activin A receptor type 2B (ACVR2B), activin A receptor type 2B (acvr2b), activin A receptor type 2B L homeolog (acvr2b.L), activin A receptor type 2B (Acvr2b), activin A receptor type 2Ba (acvr2ba), activin receptor IIB (Acvr2b), actr-iib, ActR-IIB, actr2b, actriib, ACTRIIB, ActRIIB, actrIIb, ACVR2B, HTX4, wu:fj97d11, XAR1Bezeichner auf Proteinebene für ACVR2B
- activin A receptor, type IIB
- activin receptor type IIB
- activin receptor type-2B-like
- activin type IIB receptor
- activin receptor type-2B
- ACTR-IIB
- testicular activin receptor IIB
- ActRIIB type II activin receptor B
- Activine receptor 2b (transmembrane serine kinase)
- activin receptor IIB
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