Recognizes GLUT2 expression on hGlut2-transfected NS0 cells but not on control transfectants. Detects Glut2 on the surface of the human intestinal cell line Caco2 in Flow Cytometry and on fixed cells in Immunocytochemistry tests. Based on Flow Cytometric tests on transfected cells, this antibody has no cross-reactivity with Human Glut1 or Human Glut3.
Kreuzreaktivität (Details)
Species reactivity (tested):Human.
Produktmerkmale
Synonyms: GLUT-2, Glucose transporter 2, Glucose transporter type 2 liver, Solute carrier family 2facilitated glucose transporter member 2
Flow Cytometry. Immunocytochemistry: 10 μg/mLImmunohistochemistry on Paraffin Sections: 10 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
0.5 mg/mL
Buffer
PBS containing 5 % Trehalose and 40 % Glycerol.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Haltbarkeit
12 months
Target
SLC2A2
(Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2))
glut2 antikoerper, wu:fb62h10 antikoerper, slc2a2 antikoerper, MGC83262 antikoerper, SLC2A2 antikoerper, GLUT2 antikoerper, GTT2 antikoerper, Glut2 antikoerper, AI266973 antikoerper, Glut-2 antikoerper, solute carrier family 2 (facilitated glucose transporter), member 2 antikoerper, solute carrier family 2 member 2 L homeolog antikoerper, solute carrier family 2 member 2 antikoerper, solute carrier family 2, facilitated glucose transporter member 2 antikoerper, slc2a2 antikoerper, slc2a2.L antikoerper, SLC2A2 antikoerper, LOC100534484 antikoerper, Slc2a2 antikoerper
Hintergrund
Glut2 belongs to the facilitative glucose transporter protein family that comprises 13 members. It is an integral membrane protein with 12 transmembrane domains. Glut2 is expressed predominantly in liver, intestine, kidney, and pancreatic beta-cells. It is a low-affinity glucose transporter that has been suggested to function as a glucose sensor in pancreatic beta-cells and facilitate either glucose uptake or efflux from cells depending on the nutritional state.Synonyms: GLUT-2, Glucose transporter 2, Glucose transporter type 2 liver, Solute carrier family 2 facilitated glucose transporter member 2