SLC2A2 Antikörper (C-Term) (PE)

Produktnummer ABIN2869074

Produktdetails anti-SLC2A2 Antikörper (PE)

Target: SLC2A2 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC2A2 Antikörper ist konjugiert mit PE

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Predicted molecular weight at ~57.5 kDa. Observed molecular weight at 60-70 kDa and 38-45 kDa.

Kreuzreaktivität: Human, Ratte

Aufreinigung: Peptide Affinity Purified

Immunogen: Synthetic peptide from the C-terminal of human GLUT2

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Kommentare:

A 1:1000 dilution of ABIN2869074 was sufficient for detection of GLUT2 on 293T Rapamycin-treated lysates using Goat anti-rabbit IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu SLC2A2

Target: SLC2A2 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2))

Andere Bezeichnung: GLUT2 (SLC2A2 Produkte)

Synonyme: glut2 antikoerper, wu:fb62h10 antikoerper, slc2a2 antikoerper, MGC83262 antikoerper, SLC2A2 antikoerper, GLUT2 antikoerper, GTT2 antikoerper, Glut2 antikoerper, AI266973 antikoerper, Glut-2 antikoerper, solute carrier family 2 (facilitated glucose transporter), member 2 antikoerper, solute carrier family 2 member 2 L homeolog antikoerper, solute carrier family 2 member 2 antikoerper, solute carrier family 2, facilitated glucose transporter member 2 antikoerper, slc2a2 antikoerper, slc2a2.L antikoerper, SLC2A2 antikoerper, LOC100534484 antikoerper, Slc2a2 antikoerper

Hintergrund: Glucose transporter 2 (GLUT2) also known as solute carrier family 2 (facilitated glucose transporter), member 2 (SLC2A2) is a transmembrane carrier protein that enables protein facilitated glucose movement across cell membranes. It is the principal transporter for transfer of glucose between liver and blood, and has a role in renal glucose reabsorption (1). Mutations in SLC2A2 lead to Fanconi-Bickel syndrome (FBS), which results in hepatorenal glycogen accumulation, proximal renal tubular dysfunction, and impaired utilization of glucose and galactose. Recent studies have shown that mutations in SLC2A2 can cause neonatal diabetes, and therefore may contribute to human insulin secretion (2). Novel SLC2A2 mutations have also been discovered and are being investigated to determine their roles in FBS as well (3).

Gen-ID: 6514

NCBI Accession: NP_000331

UniProt: P11168

Pathways: Warburg Effekt