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TRKA Antikörper (pTyr791)

Name: TRKA Antikörper (pTyr791)
SKU: ABIN389679
Price: 445.5 EUR
Availability: InStock

NTRK1 Reaktivität: Human WB, DB Wirt: Kaninchen Polyclonal RB16571-RB06984 unconjugated

Western blot analysis of lysates from A431 cell line, untreated or treated with EGF, 100 ng/mL, using Phospho-TrkA Antibody (ABIN389679 and ABIN2839650) (upper) or Beta-Tubulin (lower). (TRKA Antikörper (pTyr791))

Dot blot analysis of anti-Phospho-TrkA- Pab (ABIN389679 and ABIN2839650) on nitrocellulose membrane. (TRKA Antikörper (pTyr791))

2 Abbildungen

Produktnummer ABIN389679

Datenblatt (PDF)

Target Alle TRKA (NTRK1) Antikörper anzeigen

TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
Bindungsspezifität
35

26

25

19

16

15

15

10

10

9

8

8

8

6

5

4

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr791
Reaktivität
237

151

144

15

4

4

1

1
Human
Wirt
246

15

3

2
Kaninchen
Passende Sekundärantikörper
Klonalität
238

27

1
Polyklonal
Konjugat
100

18

15

13

11

11

11

11

11

11

8

6

6

6

6

6

6

2

2

1

1

1

1

1

1
Dieser TRKA Antikörper ist unkonjugiert
Applikation
183

99

79

78

50

38

30

20

19

14

7

6

4

3

2

2

2

1
Western Blotting (WB), Dot Blot (DB)

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This TrkA Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y791 of human TrkA.

Klon

RB16571-RB06984

Isotyp

Ig Fraction

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anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) antibody
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anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (Extracellular Domain) antibody
NTRK1 Reaktivität: Human WB, ELISA, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (C-Term) antibody
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anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (AA 769-796) antibody
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anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) antibody
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anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (2nd Extracellular Domain), (AA 342-356) antibody
NTRK1 Reaktivität: Human, Maus, Ratte WB, IHC, IF, FACS, ICC, LCI Wirt: Kaninchen Polyclonal unconjugated

anti-Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (pTyr496) antibody
NTRK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:1000. DB: 1:500

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Target

TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))

Andere Bezeichnung

TrkA (NTRK1 Produkte)

Synonyme

MTC antikoerper, TRK antikoerper, TRK1 antikoerper, TRKA antikoerper, Trk-A antikoerper, p140-TrkA antikoerper, CDHF12 antikoerper, CDHR16 antikoerper, HSCR1 antikoerper, MEN2A antikoerper, MEN2B antikoerper, MTC1 antikoerper, PTC antikoerper, RET-ELE1 antikoerper, RET51 antikoerper, Trk antikoerper, C80751 antikoerper, Tkr antikoerper, TrkA antikoerper, trk antikoerper, trka antikoerper, CTRKA antikoerper, trkA antikoerper, neurotrophic receptor tyrosine kinase 1 antikoerper, ret proto-oncogene antikoerper, neurotrophic tyrosine kinase, receptor, type 1 antikoerper, NTRK1 antikoerper, RET antikoerper, Ntrk1 antikoerper, ntrk1 antikoerper

Hintergrund

TrkA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TrkA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.

Molekulargewicht

87497

Gen-ID

4914

NCBI Accession

NP_001007793, NP_001012331, NP_002520

UniProt

P04629

Pathways

RTK Signalweg, Neurotrophin Signalübertragung, cAMP Metabolic Process