TRKA Produkte
(Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
Kategorien
This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008].
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Ausgewählte TRKA Kategorien
TRKA Antikörper
High quality antibodies with extensive validation data.
TRKA ELISA Kits
Reliable ELISA kits for a wide range of species.
TRKA Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene TRKA Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC
Validierungen
- (1)
- (11)
Kat. Nr.
ABIN6256787
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro)
Validierungen
- (1)
- (5)
Kat. Nr.
ABIN726110
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7155192
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene TRKA ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968899
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968898
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN1720665
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene TRKA Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf9)
Validierungen
- (2)
Kat. Nr.
ABIN5570030
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Rat
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN7321090
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN7320045
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren TRKA Produkten
: "Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA." in: Cell reports, Vol. 26, Issue 13, pp. 3522-3536.e5, (2019) (PubMed).: "Oligo-Porphyran Ameliorates Neurobehavioral Deficits in Parkinsonian Mice by Regulating the PI3K/Akt/Bcl-2 Pathway." in: Marine drugs, Vol. 16, Issue 3, (2018) (PubMed).
: "Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells." in: Scientific reports, Vol. 8, Issue 1, pp. 603, (2018) (PubMed).
: "Characterization of TRKA signaling in acute myeloid leukemia." in: Oncotarget, Vol. 9, Issue 53, pp. 30092-30105, (2018) (PubMed).
: "Cytoplasmic TrkA Expression as a Screen for Detecting NTRK1 Fusions in Colorectal Cancer." in: Translational oncology, Vol. 11, Issue 3, pp. 764-770, (2018) (PubMed).
: "OCD-like behavior is caused by dysfunction of thalamo-amygdala circuits and upregulated TrkB/ERK-MAPK signaling as a result of SPRED2 deficiency." in: Molecular psychiatry, (2017) (PubMed).
: "Nanoparticles increase human bronchial epithelial cell susceptibility to respiratory syncytial virus infection via nerve growth factor-induced autophagy." in: Physiological reports, Vol. 5, Issue 13, (2017) (PubMed).
: "Endophilin marks and controls a clathrin-independent endocytic pathway." in: Nature, Vol. 517, Issue 7535, pp. 460-5, (2015) (PubMed).
: "The interactions between nerve growth factor and gonadotrophins in bovine oviduct." in: Animal reproduction science, Vol. 149, Issue 3-4, pp. 117-23, (2014) (PubMed).
: "Humoral activity of cord blood-derived stem/progenitor cells: implications for stem cell-based adjuvant therapy of neurodegenerative disorders." in: PLoS ONE, Vol. 8, Issue 12, pp. e83833, (2014) (PubMed).
Synonyme und alternative Namen zu TRKA
neurotrophic receptor tyrosine kinase 1 (NTRK1), ret proto-oncogene (RET), neurotrophic receptor tyrosine kinase 1 (Ntrk1), neurotrophic tyrosine kinase, receptor, type 1 (Ntrk1), neurotrophic tyrosine kinase, receptor, type 1 (ntrk1), C80751, CDHF12, CDHR16, CTRKA, HSCR1, MEN2A, MEN2B, MTC, MTC1, p140-TrkA, PTC, RET-ELE1, RET51, Tkr, TRK, Trk, trk, Trk-A, TRK1, TRKA, TrkA, trka, trkABezeichner auf Proteinebene für TRKA
- Oncogene TRK
- TRK1-transforming tyrosine kinase protein
- gp140trk
- high affinity nerve growth factor receptor
- tropomyosin-related kinase A
- tyrosine kinase receptor A
- RET transforming sequence
- cadherin family member 12
- cadherin-related family member 16
- hydroxyaryl-protein kinase
- proto-oncogene c-Ret
- proto-oncogene tyrosine-protein kinase receptor Ret
- receptor tyrosine kinase
- ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)
- TrkA neurotrophin receptor
- p140-TrkA
- slow nerve growth factor receptor
- trk
- trk-A
- trkA proto-oncogene receptor
- neurotrophic tyrosine kinase receptor type 1
- tropomyosin receptor kinase
- neurotrophic tyrosine kinase, receptor, type 1
- high affinity nerve growth factor receptor-like
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